ZFIN ID: ZDB-GENE-980526-561
Gene Name: myogenic differentiation 1
Gene Symbol: myod1    Nomenclature History

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Previous Names: MyoD1 (1), MyoD (1), myod, etID309723.25 (1), wu:fb57a01, zgc:136744

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and promoter-specific chromatin binding activity. Involved in muscle organ development. Localizes to nucleus. Is expressed in several structures, including head; mesoderm; musculature system; presumptive mesoderm; and trunk. Orthologous to human MYOD1 (myogenic differentiation 1).
Genome Resources: Alliance (1),  Gene:30513 (1),  Ensembl(GRCz11):ENSDARG00000030110 (1)
GENE EXPRESSION
All Expression Data: 649 figures from 493 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh261 Point Mutation Unknown Premature Stop ENU
  • China Zebrafish Resource Center (CZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hu2023 Point Mutation Unknown Premature Stop ENU
    hu2024 Point Mutation Unknown Premature Stop ENU
    myod1_unrecovered Point Mutation Unknown Unknown ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-myod1 N/A 21
    MO2-myod1 N/A 1
    MO3-myod1 N/A 1
    MO4-myod1 N/A 1
    MO5-myod1 N/A 1
    MO6-myod1 N/A 2
    MO7-myod1 N/A 1
    MO8-myod1 N/A 1
    TALEN1-myod1
    1
    DISEASE ASSOCIATED WITH myod1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH myod1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process muscle organ development (more)
    Cellular Component NOT   nucleoplasm (more)
    Molecular Function protein binding (more)
    GO Terms (all 29)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA myod1-201 (1)    Ensembl 1772
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-myod1 polyclonal Rabbit IHC, WB Santa Cruz Biotechnology, Inc.
    10
    Ab2-myod1 polyclonal Rabbit 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM myod1
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(Hsa.MYOD1-myod1:EGFP) myod1 EGFP Danio rerioHomo sapiens 1 4
    TgBAC(myod1:EGFP) myod1 EGFP Danio rerio 1 3
    MARKER RELATIONSHIPS
    myod1 Contained in: [BAC] CH211-201M7 (1)
    myod1 Encodes: [EST] fb57a01
    [cDNA] MGC:136744 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131262 (1) 1762 nt
    Genomic GenBank:BX004812 (1) 189554 nt
    Select Tool
    Polypeptide UniProtKB:Q90477 (1) 275 aa
    Sequence Information (all 16)
    ORTHOLOGY for myod1 ( Chr: 25 )
    CITATIONS (900)