zfp36l2

ID

ZDB-GENE-030131-5873

Name

ZFP36 like 2 zinc finger CCCH-type

Symbol

zfp36l2 Nomenclature History

Previous Names

fi22c11
wu:fi22c11
zgc:76924

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable mRNA 3'-UTR AU-rich region binding activity; mRNA regulatory element binding translation repressor activity; and protein-RNA sequence-specific adaptor activity. Acts upstream of or within cranial skeletal system development. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytosol. Is expressed in head; post-vent region; telencephalon; and trunk. Orthologous to human ZFP36L2 (ZFP36 like 2 zinc finger CCCH-type).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Sun et al., 2024
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With zfp36l2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Oocyte/zygote/embryo maturation arrest 13	620154

Associated With zfp36l2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000571	Zinc finger, CCCH-type
Domain	IPR007635	Tis11B-like protein, N-terminal
Family	IPR045877	RNA-binding protein ZFP36-like
Homologous_superfamily	IPR036855	Zinc finger, CCCH-type superfamily