header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-160427-6
Ahuja et al., 2016 - Id4 functions downstream of Bmp signaling to restrict TCF function in endocardial cells during atrioventricular valve development. Developmental Biology   412(1):71-82 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage: Long-pec
PHENOTYPE:
Fish:
Observed In:
Stage: Long-pec

Fig. 5

Expression of Alcam in AV endocardial cells is expanded in id4 mutants. Alcam positive AV endocardial cells (yellow) were found to be increased in id4 mutants (B) as compared to their id4 heterozygous siblings (A) at 52 hpf. (C) Quantification of Alcam positive AV endocardial cells. (A, Atrium; AVC, Atrioventricular Canal; V, Ventricle; SAV, Superior AVC; IAV, Inferior AVC). Scale bars, 20 µm. p-value **- 0.0016, *- 0.0114. (Green – Alcam; Red - Tg(kdrl:ras-mCherry).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
alcama s896Tg control Long-pec atrioventricular canal endocardium cell IHC
s896Tg ; id4bns18/bns18 control Long-pec atrioventricular canal endocardium cell IHC
mCherry s896Tg control Long-pec atrioventricular canal endocardium IHC
s896Tg ; id4bns18/bns18 control Long-pec atrioventricular canal endocardium IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
s896Tg ; id4bns18/bns18 control Long-pec atrioventricular canal endocardium cell alcama expression increased distribution, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 412(1), Ahuja, S., Dogra, D., Stainier, D.Y., Reischauer, S., Id4 functions downstream of Bmp signaling to restrict TCF function in endocardial cells during atrioventricular valve development, 71-82, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.