ZFIN ID: ZDB-FIG-160217-10
Xu et al., 2015 - L-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome. Human molecular genetics   24(6):1540-55 Full text @ Hum. Mol. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibody:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: Prim-5
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Day 5

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
tp53 Ab7-tp53 WT control Prim-5 whole organism WB
Ab7-tp53 WT + MO1-smc3 standard conditions Prim-5 whole organism WB
Ab7-tp53 WT + MO2-rad21a standard conditions Prim-5 whole organism WB
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-nipbla + MO1-nipblb standard conditions Prim-5 eye decreased size, abnormal
Prim-5 head decreased size, abnormal
Prim-5 post-vent region curved, abnormal
Prim-5 whole organism decreased length, abnormal
Long-pec - Day 5 eye decreased size, abnormal
Long-pec - Day 5 head decreased size, abnormal
Long-pec - Day 5 heart edematous, abnormal
Long-pec - Day 5 post-vent region curved, abnormal
Long-pec - Day 5 whole organism decreased length, abnormal
WT + MO1-smc3 standard conditions Prim-5 eye decreased size, abnormal
Prim-5 head decreased size, abnormal
Prim-5 post-vent region curved, abnormal
Prim-5 whole organism decreased length, abnormal
Prim-5 whole organism tp53 expression increased amount, abnormal
Long-pec - Day 5 eye decreased size, abnormal
Long-pec - Day 5 head decreased size, abnormal
Long-pec - Day 5 heart edematous, abnormal
Long-pec - Day 5 post-vent region curved, abnormal
Long-pec - Day 5 whole organism decreased length, abnormal
WT + MO2-rad21a standard conditions Prim-5 eye decreased size, abnormal
Prim-5 head decreased size, abnormal
Prim-5 post-vent region curved, abnormal
Prim-5 whole organism decreased length, abnormal
Prim-5 whole organism tp53 expression increased amount, abnormal
Long-pec - Day 5 eye decreased size, abnormal
Long-pec - Day 5 head decreased size, abnormal
Long-pec - Day 5 heart edematous, abnormal
Long-pec - Day 5 post-vent region curved, abnormal
Long-pec - Day 5 whole organism decreased length, abnormal
Full text @ Hum. Mol. Genet.