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General Information
ZIRC
ZFIN ID: ZDB-FIG-160217-22
Xu et al., 2015 - L-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome. Human molecular genetics   24(6):1540-55 Full text @ Hum. Mol. Genet.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-nipbla + MO1-nipblb standard conditions Long-pec head apoptotic process increased occurrence, abnormal
Long-pec post-vent region apoptotic process increased occurrence, abnormal
WT + MO1-nipbla + MO1-nipblb chemical treatment: L-leucine zwitterion Long-pec head apoptotic process increased occurrence, ameliorated
Long-pec post-vent region apoptotic process increased occurrence, ameliorated
WT + MO1-smc3 standard conditions Long-pec head apoptotic process increased occurrence, abnormal
Long-pec post-vent region apoptotic process increased occurrence, abnormal
WT + MO1-smc3 chemical treatment: L-leucine zwitterion Long-pec head apoptotic process increased occurrence, ameliorated
Long-pec post-vent region apoptotic process increased occurrence, ameliorated
WT + MO2-rad21a standard conditions Long-pec head apoptotic process increased occurrence, abnormal
Long-pec post-vent region apoptotic process increased occurrence, abnormal
WT + MO2-rad21a chemical treatment: L-leucine zwitterion Long-pec head apoptotic process increased occurrence, ameliorated
Long-pec post-vent region apoptotic process increased occurrence, ameliorated
Full text @ Hum. Mol. Genet.