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Research
General Information
ZIRC
ZFIN ID: ZDB-FISH-160217-3
Fish name: WT + MO1-smc3
Genotype: WT
Targeting Reagent: MO1-smc3
HUMAN DISEASE MODELED by WT + MO1-smc3
Human Disease Conditions Citations
Cornelia de Lange syndrome standard conditions Xu et al., 2015
GENE EXPRESSION
Gene expression in WT + MO1-smc3
RNA expression
Expressed Gene Structure Conditions Figures
tp53 standard conditions Fig. 1 from Xu et al., 2015
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab7-tp53 tp53 standard conditions Fig. 1 from Xu et al., 2015
Reporter gene expression No data available
PHENOTYPE
Phenotype in WT + MO1-smc3
Phenotype Conditions Figures
cranial cartilage cartilage development decreased process quality, ameliorated chemical treatment: L-leucine zwitterion Fig. 5 from Xu et al., 2015
cranial cartilage cartilage development disrupted, abnormal standard conditions Fig. 5 from Xu et al., 2015
eye decreased size, abnormal standard conditions Fig. 1 from Xu et al., 2015
eye decreased size, ameliorated chemical treatment: L-leucine zwitterion Fig. 2 from Xu et al., 2015
head decreased size, abnormal standard conditions Fig. 1 from Xu et al., 2015
head decreased size, ameliorated chemical treatment: L-leucine zwitterion Fig. 2 from Xu et al., 2015
head apoptotic process increased occurrence, abnormal standard conditions Fig. 6 from Xu et al., 2015
head apoptotic process increased occurrence, ameliorated chemical treatment: L-leucine zwitterion Fig. 6 from Xu et al., 2015
heart edematous, abnormal standard conditions Fig. 1 from Xu et al., 2015
post-vent region curved, abnormal standard conditions Fig. 1 from Xu et al., 2015
post-vent region curved, ameliorated chemical treatment: L-leucine zwitterion Fig. 2 from Xu et al., 2015
post-vent region apoptotic process increased occurrence, abnormal standard conditions Fig. 6 from Xu et al., 2015
post-vent region apoptotic process increased occurrence, ameliorated chemical treatment: L-leucine zwitterion Fig. 6 from Xu et al., 2015
rRNA transcription decreased process quality, abnormal standard conditions Fig. 4 from Xu et al., 2015
rRNA transcription decreased process quality, ameliorated chemical treatment: L-leucine zwitterion Fig. 4 from Xu et al., 2015
translation decreased process quality, abnormal standard conditions Fig. 3Fig. 4 from Xu et al., 2015
translation decreased process quality, ameliorated chemical treatment: L-leucine zwitterion Fig. 3Fig. 4 from Xu et al., 2015
trunk decreased length, ameliorated chemical treatment: L-leucine zwitterion Fig. 2 from Xu et al., 2015
whole organism decreased length, abnormal standard conditions Fig. 1 from Xu et al., 2015
whole organism tp53 expression increased amount, abnormal standard conditions Fig. 1 from Xu et al., 2015
whole organism lethal (sensu genetics), abnormal standard conditions Fig. S4 from Xu et al., 2015
whole organism lethal (sensu genetics), ameliorated chemical treatment: L-leucine zwitterion Fig. S4 from Xu et al., 2015

CITATIONS  (1)