ZFIN ID: ZDB-FIG-160217-19
Xu et al., 2015 - L-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome. Human molecular genetics   24(6):1540-55 Full text @ Hum. Mol. Genet.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Prim-5

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-nipbla + MO1-nipblb standard conditions Prim-5 rRNA transcription decreased process quality, abnormal
Prim-5 translation decreased process quality, abnormal
WT + MO1-nipbla + MO1-nipblb chemical treatment: L-leucine zwitterion Prim-5 rRNA transcription decreased process quality, ameliorated
Prim-5 translation decreased process quality, ameliorated
WT + MO1-smc3 standard conditions Prim-5 rRNA transcription decreased process quality, abnormal
Prim-5 translation decreased process quality, abnormal
WT + MO1-smc3 chemical treatment: L-leucine zwitterion Prim-5 rRNA transcription decreased process quality, ameliorated
Prim-5 translation decreased process quality, ameliorated
WT + MO2-rad21a standard conditions Prim-5 rRNA transcription decreased process quality, abnormal
Prim-5 translation decreased process quality, abnormal
WT + MO2-rad21a chemical treatment: L-leucine zwitterion Prim-5 rRNA transcription decreased process quality, ameliorated
Prim-5 translation decreased process quality, ameliorated
Full text @ Hum. Mol. Genet.