ZFIN ID: ZDB-FIG-160217-20
Xu et al., 2015 - L-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome. Human molecular genetics   24(6):1540-55 Full text @ Hum. Mol. Genet.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Day 5

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-nipbla + MO1-nipblb standard conditions Day 5 cranial cartilage cartilage development disrupted, abnormal
WT + MO1-nipbla + MO1-nipblb chemical treatment: L-leucine zwitterion Day 5 cranial cartilage cartilage development decreased process quality, ameliorated
WT + MO1-smc3 standard conditions Day 5 cranial cartilage cartilage development disrupted, abnormal
WT + MO1-smc3 chemical treatment: L-leucine zwitterion Day 5 cranial cartilage cartilage development decreased process quality, ameliorated
WT + MO2-rad21a standard conditions Day 5 cranial cartilage cartilage development disrupted, abnormal
WT + MO2-rad21a chemical treatment: L-leucine zwitterion Day 5 cranial cartilage cartilage development decreased process quality, ameliorated
rad21ahi2529Tg standard conditions Day 5 cranial cartilage cartilage development disrupted, abnormal
rad21ahi2529Tg chemical treatment: L-leucine zwitterion Day 5 cranial cartilage cartilage development decreased process quality, ameliorated
smc1alhi1113aTg standard conditions Day 5 cranial cartilage cartilage development disrupted, abnormal
smc1alhi1113aTg chemical treatment: L-leucine zwitterion Day 5 cranial cartilage cartilage development decreased process quality, ameliorated
Full text @ Hum. Mol. Genet.