ZFIN ID: ZDB-FIG-151120-20
Won et al., 2015 - Lnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreas. Proceedings of the National Academy of Sciences of the United States of America   112(40):12426-31 Full text @ Proc. Natl. Acad. Sci. USA
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage Range: Prim-25 to Long-pec
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Prim-25 to Long-pec

Fig. S7 Lnx2a-MO injection affects both the specification and expansion of the ventral pancreas. Lnx2a-MO injection leads to inhibition of the ventral pancreas markers (ptf1a, mnr2a) from 36 hpf onward. HB, hindbrain; SC, spinal cord.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
mnx2a AB control Prim-25 anterior pancreatic bud ISH
Long-pec anterior pancreatic bud ISH
AB + MO1-lnx2a control Prim-25 anterior pancreatic bud ISH
Long-pec anterior pancreatic bud ISH
ptf1a AB control Prim-25 anterior pancreatic bud ISH
Long-pec anterior pancreatic bud ISH
AB + MO1-lnx2a control Prim-25 anterior pancreatic bud ISH
Long-pec anterior pancreatic bud ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-lnx2a control Prim-25 anterior pancreatic bud mnx2a expression decreased distribution, abnormal
Prim-25 anterior pancreatic bud ptf1a expression decreased distribution, abnormal
Prim-25 exocrine pancreas development decreased process quality, abnormal
Long-pec anterior pancreatic bud mnx2a expression decreased distribution, abnormal
Long-pec anterior pancreatic bud ptf1a expression decreased distribution, abnormal
Long-pec exocrine pancreas development decreased process quality, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Proceedings of the National Academy of Sciences of the United States of America for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Proc. Natl. Acad. Sci. USA