|ZFIN ID: ZDB-FIG-120601-51|
Fig. 5 Histology of the obese transformed Tg (krt4:Hsa.myrAkt1)cy18.
(A) Schematic diagram showing the relative positions (red dotted boxes) for histological sections from B to I. Histological assessment of dorsal muscle tissues (B and C), visceral adipocytes (D and E), gill arch (F and G) and bone tissues in the tail (H and I) for WT and Tg aged 3 mpf. The paraffin sections in B to G were stained with Periodic acid-Schiff, and bone tissues in the tail regions (H&I) were stained with Masson’s trichrome. Comparison adipocyte average size (J), adipocyte numbers (K), and adipocyte size distribution histogram (L) between WT and Tg. Stars above the error bars indicate significant differences as tested by Student’s t-test (*p<0.05, **p<0.01, and ***p<0.001). WT, wild type; Tg, Tg(krt4:Hsa.myrAkt1)cy18; mpf, month post-fertilization.
|cy18Tg||standard conditions||Adult||fat cell located in pharyngeal arch 3-7, abnormal|
|Adult||fat cell located in trunk musculature, abnormal|
|Adult||fat cell located in vertebral column, abnormal|
|Adult||hypodermis adipose tissue mislocalised, abnormal|
|Adult||pharyngeal arch adipose tissue mislocalised, abnormal|
|Adult||pleuroperitoneal cavity fat cell increased amount, abnormal|
|Adult||pleuroperitoneal cavity fat cell size, normal|
|Adult||trunk musculature adipose tissue mislocalised, abnormal|
|Adult||vertebral column adipose tissue mislocalised, abnormal|
|Acknowledgments:||ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One|