ZFIN ID: ZDB-FIG-070219-16
Hernandez et al., 2007 - Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development. Development (Cambridge, England)   134(1):177-187 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
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Anatomical Terms:
Stage: 1-4 somites

Fig. S2 The ventral hindbrain is sensitive to low concentrations of RA. RNA in situ hybridizations showing vhnf1 (blue), and krox20 and pax2a (both in red) expression at the 3-somite stage (11 hpf). In embryos treated with 10 nM RA, which causes very mild, if any, patterning defects, the ventral-most hindbrain is specifically posteriorized, corresponding with the absence of cyp26c1 expression there (arrow in B). Scale bar: 100 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
egr2b cyp26a1rw716/rw716 chemical treatment: all-trans-retinoic acid 1-4 somites presumptive rhombomere 3 ISH
1-4 somites presumptive rhombomere 5 ISH
hnf1ba cyp26a1rw716/rw716 chemical treatment: all-trans-retinoic acid 1-4 somites presumptive rhombomere 6 ISH
1-4 somites presumptive rhombomere 7 ISH
1-4 somites presumptive rhombomere 8 ISH
pax2a cyp26a1rw716/rw716 chemical treatment: all-trans-retinoic acid 1-4 somites midbrain hindbrain boundary neural keel ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development