ZFIN ID: ZDB-GENE-020104-1
Gene Name: HNF1 homeobox Ba
Gene Symbol: hnf1ba
Sequence Ontology ID : SO:0000704

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Previous Names: hnf1b (1), hob, vhnf1 (2), chunp6877, mst, tcf2 (1), transcription factor 2

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(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA binding activity, DNA-binding activity transcription factor activity, and protein dimerization activity; involved in several processes, including animal organ development,  ...
GENE EXPRESSION
All Expression Data: 45 figures from 30 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi548Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi1843Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi2169Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la550 Unknown Unknown Unknown ENU
    la1146 Unknown Unknown Unknown ENU
    la019161Tg Transgenic Insertion Unknown Unknown DNA
    s430 Point Mutation Unknown Missense ENU
    s917 Point Mutation Unknown Premature Stop ENU
    sa10100 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • wi408 Unknown Unknown Unknown
    Targeting reagents:
    PHENOTYPE
    Data: 40 figures from 19 publications
    Observed in:
    DISEASE ASSOCIATED WITH hnf1ba HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    maturity-onset diabetes of the young type 5 Renal cysts and diabetes syndrome 137920
    nonpapillary renal cell carcinoma {Renal cell carcinoma} 144700
    type 2 diabetes mellitus Diabetes mellitus, noninsulin-dependent 125853
    DISEASE ASSOCIATED WITH hnf1ba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endoderm formation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 35)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR006897 (1)
  • InterPro:IPR006899 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR010982 (1)
  • InterPro:IPR023219 (1)
  • InterPro:IPR039066 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF04812 (1)
  • Pfam:PF04814 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hnf1ba-001 (1) 4167
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hnf1ba No data available
    MARKER RELATIONSHIPS
    hnf1baContained in: [BAC] DKEYP-118E10 (1)
    hnf1baEncodes: [EST] af244140 (1)
    [cDNA] MGC:158167 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131880 (1) 4167bp
    Genomic GenBank:BX511308 (1) 123109bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IR44 (1) 559aa
    Sequence Clusters UniGene:118179 (1)
    Sequence Information (all 29)
    OTHER hnf1ba GENE PAGES
  • Alliance (1)
  • Gene:792391 (1)
  • VEGA:OTTDARG00000020727 (1)
  • ORTHOLOGY for hnf1ba (Chr: 15)
    CITATIONS (86)