ZFIN ID: ZDB-FIG-070219-15
Hernandez et al., 2007 - Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development. Development (Cambridge, England)   134(1):177-187 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Term:
Stage: 14-19 somites

Fig. 6 cyp26a1 protects against teratogenic effects of the RA precursor retinal. Wild-type (A) and cyp26a1-/- (B) embryos injected with 20 pmol retinal at the one-cell stage. Wild-type embryos are only mildly affected by approximately triple the normal levels of retinal, whereas cyp26 mutants are Strongly posteriorized, with hoxd4 expression extending throughout the brain. Scale bar: 100 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
egr2b cyp26a1rw716/rw716 chemical treatment: all-trans-retinal 14-19 somites Not Detected brain ISH
hoxd4a cyp26a1rw716/rw716 chemical treatment: all-trans-retinal 14-19 somites hindbrain ISH
pax2a cyp26a1rw716/rw716 chemical treatment: all-trans-retinal 14-19 somites Not Detected brain ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development