Dernovšek, J., Zajec, Ž., Poje, G., Urbančič, D., Sturtzel, C., Goričan, T., Grissenberger, S., Ciura, K., Woziński, M., Gedgaudas, M., Zubrienė, A., Grdadolnik, S.G., Mlinarič-Raščan, I., Rajić, Z., Cotman, A.E., Zidar, N., Distel, M., Tomašič, T. (2024) Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 177:116941116941
|
Schmitner, N., Thumer, S., Regele, D., Mayer, E., Bergerweiss, I., Helker, C., Stainier, D.Y.R., Meyer, D., Kimmel, R.A. (2024) Conserved glucokinase regulation in zebrafish confirms therapeutic utility for pharmacologic modulation in diabetes. Communications biology. 7:15571557
|
Yen, J.H., Keak, P.Y., Wu, C.L., Chen, H.J., Gao, W.Y., Liou, J.W., Chen, Y.R., Lin, L.I., Chen, P.Y. (2024) Shikonin, a natural naphthoquinone phytochemical, exerts anti-leukemia effects in human CBF-AML cell lines and zebrafish xenograft models. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 179:117395117395
|
Banu, S., Gaur, N., Nair, S., Ravikrishnan, T., Khan, S., Mani, S., Bharathi, S., Mandal, K., Kuram, N.A., Vuppaladadium, S., Ravi, R., Murthy, C.L.N., Quoseena, M., Babu, N.S., Idris, M.M. (2022) Transcriptomic and proteomic analysis of epimorphic regeneration in zebrafish caudal fin tissue. Genomics. 114(2):110300
|
|
Gabler, L., Jaunecker, C.N., Katz, S., van Schoonhoven, S., Englinger, B., Pirker, C., Mohr, T., Vician, P., Stojanovic, M., Woitzuck, V., Laemmerer, A., Kirchhofer, D., Mayr, L., LaFranca, M., Erhart, F., Grissenberger, S., Wenninger-Weinzierl, A., Sturtzel, C., Kiesel, B., Lang, A., Marian, B., Grasl-Kraupp, B., Distel, M., Schüler, J., Gojo, J., Grusch, M., Spiegl-Kreinecker, S., Donoghue, D.J., Lötsch, D., Berger, W. (2022) Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness. Acta neuropathologica communications. 10:65
|
Grissenberger, S., Sturtzel, C., Wenninger-Weinzierl, A., Radic-Sarikas, B., Scheuringer, E., Bierbaumer, L., Etienne, V., Némati, F., Pascoal, S., Tötzl, M., Tomazou, E., Metzelder, M., Putz, E.M., Decaudin, D., Delattre, O., Surdez, D., Kovar, H., Halbritter, F., Distel, M. (2022) High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-XL inhibition against Ewing sarcoma. Cancer letters. 554:216028
|
|
|
Gronseth, E., Gupta, A., Koceja, C., Kumar, S., Kutty, R.G., Rarick, K., Wang, L., Ramchandran, R. (2020) Astrocytes influence medulloblastoma phenotypes and CD133 surface expression. PLoS One. 15:e0235852
|
Haindl, R., Deloria, A.J., Sturtzel, C., Sattmann, H., Rohringer, W., Fischer, B., Andreana, M., Unterhuber, A., Schwerte, T., Distel, M., Drexler, W., Leitgeb, R., Liu, M. (2020) Functional optical coherence tomography and photoacoustic microscopy imaging for zebrafish larvae. Biomedical Optics Express. 11:2137-2151
|
Pascoal, S., Salzer, B., Scheuringer, E., Wenninger-Weinzierl, A., Sturtzel, C., Holter, W., Taschner-Mandl, S., Lehner, M., Distel, M. (2020) A Preclinical Embryonic Zebrafish Xenograft Model to Investigate CAR T Cells In Vivo. Cancers. 12(3):
|
Siregar, P., Juniardi, S., Audira, G., Lai, Y.H., Huang, J.C., Chen, K.H., Chen, J.R., Hsiao, C.D. (2020) Method Standardization for Conducting Innate Color Preference Studies in Different Zebrafish Strains. Biomedicines. 8(8):
|
Yamanaka, M., Iwata, H., Masuda, K., Araki, M., Okuno, Y., Okamura, M., Koiwa, J., Tanaka, T. (2020) A novel orexin antagonist from a natural plant was discovered using zebrafish behavioural analysis. European review for medical and pharmacological sciences. 24:5127-5139
|
Camargo-Sosa, K., Colanesi, S., Müller, J., Schulte-Merker, S., Stemple, D., Patton, E.E., Kelsh, R.N. (2019) Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish. PLoS Genetics. 15:e1007941
|
|
|
Tiek, D.M., Khatib, S.A., Trepicchio, C.J., Heckler, M.M., Divekar, S.D., Sarkaria, J.N., Glasgow, E., Riggins, R.B. (2019) Estrogen-related receptor β activation and isoform shifting by cdc2-like kinase inhibition restricts migration and intracranial tumor growth in glioblastoma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33:13476-13491
|
Tilghman, J.M., Ling, A.Y., Turner, T.N., Sosa, M.X., Krumm, N., Chatterjee, S., Kapoor, A., Coe, B.P., Nguyen, K.H., Gupta, N., Gabriel, S., Eichler, E.E., Berrios, C., Chakravarti, A. (2019) Molecular Genetic Anatomy and Risk Profile of Hirschsprung's Disease. The New England Journal of Medicine. 380:1421-1432
|
Xue, Y., Liu, D., Cui, G., Ding, Y., Ai, D., Gao, S., Zhang, Y., Suo, S., Wang, X., Lv, P., Zhou, C., Li, Y., Chen, X., Peng, G., Jing, N., Han, J.J., Liu, F. (2019) A 3D Atlas of Hematopoietic Stem and Progenitor Cell Expansion by Multi-dimensional RNA-Seq Analysis. Cell Reports. 27:1567-1578.e5
|
Spiewak, J.E., Bain, E.J., Liu, J., Kou, K., Sturiale, S.L., Patterson, L.B., Diba, P., Eisen, J.S., Braasch, I., Ganz, J., Parichy, D.M. (2018) Evolution of Endothelin signaling and diversification of adult pigment pattern in Danio fishes. PLoS Genetics. 14:e1007538
|
Ciarlo, C., Kaufman, C.K., Kinikoglu, B., Michael, J., Yang, S., D Amato, C., Blokzijl-Franke, S., den Hertog, J., Schlaeger, T.M., Zhou, Y., Liao, E., Zon, L.I. (2017) A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. eLIFE. 6
|
Haindl, R., Preisser, S., Andreana, M., Rohringer, W., Sturtzel, C., Distel, M., Chen, Z., Rank, E., Fischer, B., Drexler, W., Liu, M. (2017) Dual modality reflection mode optical coherence and photoacoustic microscopy using an akinetic sensor. Optics letters. 42:4319-4322
|
Heffer, A., Marquart, G.D., Aquilina-Beck, A., Saleem, N., Burgess, H.A., Dawid, I.B. (2017) Generation and characterization of Kctd15 mutations in zebrafish. PLoS One. 12:e0189162
|
Huang, S.J., Cheng, C.L., Chen, J.R., Gong, H.Y., Liu, W., Wu, J.L. (2017) Inducible liver-specific overexpression of gankyrin in zebrafish results in spontaneous intrahepatic cholangiocarcinoma and hepatocellular carcinoma formation. Biochemical and Biophysical Research Communications. 490(3):1052-1058
|
Li, J., Casteels, T., Frogne, T., Ingvorsen, C., Honoré, C., Courtney, M., Huber, K.V., Schmitner, N., Kimmel, R.A., Romanov, R.A., Sturtzel, C., Lardeau, C.H., Klughammer, J., Farlik, M., Sdelci, S., Vieira, A., Avolio, F., Briand, F., Baburin, I., Májek, P., Pauler, F.M., Penz, T., Stukalov, A., Gridling, M., Parapatics, K., Barbieux, C., Berishvili, E., Spittler, A., Colinge, J., Bennett, K.L., Hering, S., Sulpice, T., Bock, C., Distel, M., Harkany, T., Meyer, D., Superti-Furga, G., Collombat, P., Hecksher-Sørensen, J., Kubicek, S. (2017) Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity.. Cell. 168(1-2):86-100.e15
|
Neiswender, J.V., Kortum, R.L., Bourque, C., Kasheta, M., Zon, L., Morrison, D.K., Ceol, C.J. (2017) KIT Suppresses BRAFV600E-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling.. Cancer research. 77(21):5820-5830
|
|
|
Frohnhöfer, H.G., Geiger-Rudolph, S., Pattky, M., Meixner, M., Huhn, C., Maischein, H.M., Geisler, R., Gehring, I., Maderspacher, F., Nüsslein-Volhard, C., Irion, U. (2016) Spermidine, but not spermine, is essential for pigment pattern formation in zebrafish. Biology Open. 5(6):736-44
|
|
Zhang, B., Shimada, Y., Hirota, T., Ariyoshi, M., Kuroyanagi, J., Nishimura, Y., Tanaka, T. (2016) Novel immunologic tolerance of human cancer cell xenotransplants in zebrafish. Translational research : the journal of laboratory and clinical medicine. 170:89-98.e3
|
Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
|
Nishimura, Y., Sasagawa, S., Ariyoshi, M., Ichikawa, S., Shimada, Y., Kawaguchi, K., Kawase, R., Yamamoto, R., Uehara, T., Yanai, T., Takata, R., Tanaka, T. (2015) Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity. Frontiers in pharmacology. 6:199
|
Zhang, B., Shimada, Y., Kuroyanagi, J., Ariyoshi, M., Nomoto, T., Shintou, T., Umemoto, N., Nishimura, Y., Miyazaki, T., Tanaka, T. (2015) In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3). Biomaterials. 52:14-25
|
|
Irion, U., Frohnhöfer, H.G., Krauss, J., Çolak Champollion, T., Maischein, H., Geiger-Rudolph, S., Weiler, C., Nüsslein-Volhard, C. (2014) Gap junctions composed of connexions 41.8 and 39.4 are essential for colour pattern formation in zebrafish. eLIFE. 4:1225-38
|
Krauss, J., Frohnhöfer, H.G., Walderich, B., Maischein, H.M., Weiler, C., Irion, U., Nüsslein-Volhard, C. (2014) Endothelin signalling in iridophore development and stripe pattern formation of zebrafish. Biology Open. 3(6):503-9
|
Shimada, Y., Kuroyanagi, J., Zhang, B., Ariyoshi, M., Umemoto, N., Nishimura, Y., and Tanaka, T. (2014) Downregulation of Max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice. International journal of obesity (2005). 38(8):1053-60
|
|
Zhang, B., Shimada, Y., Kuroyanagi, J., Umemoto, N., Nishimura, Y., and Tanaka, T. (2014) Quantitative phenotyping-based in vivo chemical screening in a zebrafish model of leukemia stem cell xenotransplantation. PLoS One. 9(1):e85439
|
|
|
Krauss, J., Astrinidis, P., Frohnhöfer, H.G., Walderich, B., and Nüsslein-Volhard, C. (2013) transparent, a gene affecting stripe formation in Zebrafish, encodes the mitochondrial protein Mpv17 that is required for iridophore survival. Biology Open. 2(7):703-710
|
Liu, M., Schmitner, N., Sandrian, M.G., Zabihian, B., Hermann, B., Salvenmoser, W., Meyer, D., and Drexler, W. (2013) In vivo three dimensional dual wavelength photoacoustic tomography imaging of the far red fluorescent protein E2-Crimson expressed in adult zebrafish. Biomedical Optics Express. 4(10):1846-1855
|
Nishimura, Y., Yata, K., Nomoto, T., Ogiwara, T., Watanabe, K., Shintou, T., Tsuboyama, A., Okano, M., Umemoto, N., Zhang, Z., Kawabata, M., Zhang, B., Kuroyanagi, J., Shimada, Y., Miyazaki, T., Imamura, T., Tomimoto, H., and Tanaka, T. (2013) Identification of a Novel Indoline Derivative for in Vivo Fluorescent Imaging of Blood-Brain Barrier Disruption in Animal Models. ACS Chemical Neuroscience. 4(8):1183-93
|
Nuster, R., Schmitner, N., Wurzinger, G., Gratt, S., Salvenmoser, W., Meyer, D., and Paltauf, G. (2013) Hybrid photoacoustic and ultrasound section imaging with optical ultrasound detection. Journal of biophotonics. 6(6-7):549-559
|
|
Colanesi, S., Taylor, K.L., Temperley, N.D., Lundegaard, P.R., Liu, D., North, T.E., Ishizaki, H., Kelsh, R.N., and Patton, E.E. (2012) Small molecule screening identifies targetable zebrafish pigmentation pathways. Pigment cell & melanoma research. 25(2):131-143
|
Watanabe, K., Nishimura, Y., Nomoto, T., Umemoto, N., Zhang, Z., Zhang, B., Kuroyanagi, J., Shimada, Y., Shintou, T., Okano, M., Miyazaki, T., Imamura, T., and Tanaka, T. (2012) In vivo assessment of the permeability of the blood--brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish. BMC Neuroscience. 13(1):101
|
|
|
White, R.M., Cech, J., Ratanasirintrawoot, S., Lin, C.Y., Rahl, P.B., Burke, C.J., Langdon, E., Tomlinson, M.L., Mosher, J., Kaufman, C., Chen, F., Long, H.K., Kramer, M., Datta, S., Neuberg, D., Granter, S., Young, R.A., Morrison, .S, Wheeler, G.N., and Zon, L.I. (2011) DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature. 471(7339):518-522
|
|
|
|
|
|
|
|
Lopes, S.S., Yang, X., Müller, J., Carney, T.J., McAdow, A.R., Rauch, G.J., Jacoby, A.S., Hurst, L.D., Delfino-Machín, M., Haffter, P., Geisler, R., Johnson, S.L., Ward, A., and Kelsh, R.N. (2008) Leukocyte tyrosine kinase functions in pigment cell development. PLoS Genetics. 4(3):e1000026
|
|
Lister, J.A., Cooper, C., Nguyen, K., Modrell, M., Grant, K., and Raible, D.W. (2006) Zebrafish Foxd3 is required for development of a subset of neural crest derivatives. Developmental Biology. 290(1):92-104
|
|
Stewart, R.A., Arduini, B.L., Berghmans, S., George, R.E., Kanki, J.P., Henion, P.D., and Look, A.T. (2006) Zebrafish foxd3 is selectively required for neural crest specification, migration and survival. Developmental Biology. 292(1):174-188
|
Quigley, I.K., Manuel, J.L., Roberts, R.A., Nuckels, R.J., Herrington, E.R., MacDonald, E.L., and Parichy, D.M. (2005) Evolutionary diversification of pigment pattern in Danio fishes: differential fms dependence and stripe loss in D. albolineatus. Development (Cambridge, England). 132(1):89-104
|
|
Cornell, R.A., Yemm, E., Bonde, G., Li, W., d'Alencon, C., Wegman, L., Eisen, J., and Zahs, A. (2004) Touchtone promotes survival of embryonic melanophores in zebrafish. Mechanisms of Development. 121(11):1365-1376
|
Bink, R.J., Habuchi, H., Lele, Z., Dolk, E., Joore, J., Rauch, G.J., Geisler, R., Wilson, S.W., den Hertog, J., Kimata, K., and Zivkovic, D. (2003) Heparan sulfate 6-O-sulfotransferase is essential for muscle development in zebrafish. The Journal of biological chemistry. 278(33):31118-31127
|
|
|
Parichy, D.M., Mellgren, E.M., Rawls, J.F., Lopes, S.S., Kelsh, R.N., and Johnson, S.L. (2000) Mutational analysis of endothelin receptor b1 (rose) during neural crest and pigment pattern development in the zebrafish Danio rerio. Developmental Biology. 227(2):294-306
|
Parichy, D.M., Ransom, D.G., Paw, B., Zon, L.I., and Johnson, S.L. (2000) An orthologue of the kit-related gene fms is required for development of neural crest-derived xanthophores and a subpopulation of adult melanocytes in the zebrafish, Danio rerio. Development (Cambridge, England). 127(14):3031-3044
|
|
Reifers, F., Adams, J., Mason, I.J., Schulte-Merker, S., and Brand, M. (2000) Overlapping and distinct functions provided by fgf17, a new zebrafish member of the Fgf8/17/18 subgroup of Fgfs. Mechanisms of Development. 99(1-2):39-49
|
Postlethwait, J.H, Yan, Y.-L., Gates, M.A., Horne, S., Amores, A., Brownlie, A., Donovan, A., Egan, E.S., Force, A., Gong, Z., Goutel, C., Fritz, A., Kelsh, R., Knapik, E., Liao, E., Paw, B., Ransom, D., Singer, A., Thomson, M., Abduljabbar, T.S., Yelick, P., Beier, D., Joly, J.-S., Larhammar, D., Rosa, F., Westerfield, M., Zon, L.I., Johnson, S.L., and Talbot, W.S. (1998) Vertebrate genome evolution and the zebrafish gene map. Nature Genetics. 18:345-349
|
Haffter, P., Odenthal, J., Mullins, M.C., Lin, S., Farrell, M.J., Vogelsang, E., Haas, F., Brand, M., van Eeden, F.J.M., Furutani-Seiki, M., Granato, M., Hammerschmidt, M., Heisenberg, C.P., Jiang, Y.J., Kane, D.A., Kelsh, R.N., Hopkins, N., and Nüsslein-Volhard, C. (1996) Mutations affecting pigmentation and shape of the adult zebrafish. Development genes and evolution. 206(4):260-276
|
|
|