Gene
ednrba
- ID
- ZDB-GENE-980526-16
- Name
- endothelin receptor Ba
- Symbol
- ednrba Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have endothelin receptor activity. Involved in iridophore differentiation and regulation of developmental pigmentation. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in gill; head; iridophore; pigment cell; and trunk. Human ortholog(s) of this gene implicated in ABCD syndrome; Hirschsprung's disease; Waardenburg's syndrome (multiple); asthma; and pulmonary hypertension. Orthologous to human EDNRB (endothelin receptor type B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 19 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ABCD syndrome | Alliance | ?ABCD syndrome | 600501 |
| Waardenburg syndrome type 4A | Alliance | Waardenburg syndrome, type 4A | 277580 |
| {Hirschsprung disease, susceptibility to, 2} | 600155 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Endothelin receptor B | Endothelin receptor family | GPCR, rhodopsin-like, 7TM | G-protein coupled endothelin receptor | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|---|
|
UniProtKB:Q9DGM2
|
426 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | ednrba-001 (1) | Havana | 1,492 nt |
Interactions and Pathways
No data available
Plasmids
No data available