ZFIN

ZFIN ID: ZDB-GENE-040426-1518

ZFIN ID: ZDB-GENE-040426-1518

CITATIONS (102 total)

Gene Name:	interferon regulatory factor 7
Gene Symbol:	irf7

An, L.L., Zhao, X., Gong, X.Y., Li, Y.L., Qu, Z.L., Sun, H.Y., Guo, W.H., Dan, C., Gui, J.F., Zhang, Y.B. (2022) Promoter Binding and Nuclear Retention Features of Zebrafish IRF Family Members in IFN Response. Frontiers in immunology. 13:861262
Boltaña, S., Rey, S., Roher, N., Vargas, R., Huerta, M., Huntingford, F.A., Goetzm, F.W., Moore, J., Garcia-Valtanen, P., Estepa, A., and Mackenzie, S. (2013) Behavioural fever is a synergic signal amplifying the innate immune response. Proceedings. Biological sciences. 280(1766):20131381
Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41
Chen, B., Li, C., Yao, J., Shi, L., Liu, W., Wang, F., Huo, S., Zhang, Y., Lu, Y., Ashraf, U., Ye, J., Liu, X. (2020) Zebrafish NIK Mediates IFN Induction by Regulating Activation of IRF3 and NF-κB. Journal of immunology (Baltimore, Md. : 1950). 204(7):1881-1891
Chen, C., Lu, M., Lin, S., Qin, W. (2020) The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond-Blackfan anemia. Cell Death & Disease. 11:135
Chen, S., Dang, Y., Gong, Z., Letcher, R.J., Liu, C. (2019) Progression of liver tumor was promoted by tris(1,3-dichloro-2-propyl) phosphate through the induction of inflammatory responses in kras^V12 transgenic zebrafish. Environmental pollution (Barking, Essex : 1987). 255:113315
Chen, S., Gong, Z., Letcher, R.J., Liu, C. (2020) Promotion effect of liver tumor progression in male kras transgenic zebrafish induced by tris (1, 3-dichloro-2-propyl) phosphate. Ecotoxicology and environmental safety. 191:110220
Chen, S., Liu, S., Wang, J., Wu, Q., Wang, A., Guan, H., Zhang, Q., Zhang, D., Wang, X., Song, H., Qin, J., Zou, J., Jiang, Z., Ouyang, S., Feng, X.H., Liang, T., Xu, P. (2020) TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology. Molecular Cell. 80:810-827.e7
Chen, S.N., Gan, Z., Nie, P. (2021) Retroposition of the Long Transcript from Multiexon IFN-β Homologs in Ancestry Vertebrate Gave Rise to the Proximal Transcription Elements of Intronless IFN-β Promoter in Humans. Journal of immunology (Baltimore, Md. : 1950). 207(10):2512-2520
Chernyavskaya, Y., Mudbhary, R., Tokarz, D., Jacob, V., Gopinath, S., Zhang, C., Sun, X., Wang, S., Magnani, E., Madakashira, B.P., Yoder, J.A., Hoshida, Y., Sadler, K.C. (2017) Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development (Cambridge, England). 144(16):2925-2939
Cui, H., Yan, Y., Wei, J., Huang, X., Huang, Y., Ouyang, Z., and Qin, Q. (2011) Identification and functional characterization of an interferon regulatory factor 7-like (IRF7-like) gene from orange-spotted grouper, Epinephelus coioides. Developmental and comparative immunology. 35(6):672-684
Danilova, N., Wilkes, M., Bibikova, E., Youn, M.Y., Sakamoto, K.M., Lin, S. (2018) Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. Scientific Reports. 8:5165
Demin, K.A., Lakstygal, A.M., Krotova, N.A., Masharsky, A., Tagawa, N., Chernysh, M.V., Ilyin, N.P., Taranov, A.S., Galstyan, D.S., Derzhavina, K.A., Levchenko, N.A., Kolesnikova, T.O., Mor, M.S., Vasyutina, M.L., Efimova, E.V., Katolikova, N., Prjibelski, A.D., Gainetdinov, R.R., de Abreu, M.S., Amstislavskaya, T.G., Strekalova, T., Kalueff, A.V. (2020) Understanding complex dynamics of behavioral, neurochemical and transcriptomic changes induced by prolonged chronic unpredictable stress in zebrafish. Scientific Reports. 10:19981
Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
Feng, H., Zhang, Q.M., Zhang, Y.B., Li, Z., Zhang, J., Xiong, Y.W., Wu, M., Gui, J.F. (2016) Zebrafish IRF1, IRF3, and IRF7 Differentially Regulate IFNΦ1 and IFNΦ3 Expression through Assembly of Homo- or Heteroprotein Complexes. Journal of immunology (Baltimore, Md. : 1950). 197(5):1893-904
Feng, H., Zhang, Y., Zhang, Q., Li, Z., Zhang, Q., Gui, J. (2015) Zebrafish IRF1 Regulates IFN Antiviral Response through Binding to IFNϕ1 and IFNϕ3 Promoters Downstream of MyD88 Signaling. Journal of immunology (Baltimore, Md. : 1950). 194(3):1225-38
Gong, X.Y., Zhang, Q.M., Zhao, X., Li, Y.L., Qu, Z.L., Li, Z., Dan, C., Gui, J.F., Zhang, Y.B. (2022) LGP2 is essential for zebrafish survival through dual regulation of IFN antiviral response. iScience. 25:104821
Guo, J., Wu, P., Cao, J., Luo, Y., Chen, J., Wang, G., Guo, W., Wang, T., He, X. (2019) The PFOS disturbed immunomodulatory functions via nuclear Factor-κB signaling in liver of zebrafish (Danio rerio). Fish & shellfish immunology. 91:87-98
Hu, S.Q., Xu, H.M., Qian, F., Chen, C.S., Wang, X., Liu, D., Cheng, L. (2021) Interferon regulatory factor-7 is required for hair cell development during zebrafish embryogenesis. Developmental Neurobiology. 82(1):88-97
Huang, B., Qi, Z.T., Xu, Z., and Nie, P. (2010) Global characterization of interferon regulatory factor (IRF) genes in vertebrates: Glimpse of the diversification in evolution. BMC immunology. 11:22
Jiang, J., Gu, J., Zhan, A., Mao, M., Liu, Y., Wang, H., Mao, Y. (2022) Cloning, Exogenous Expression and Function Analysis of Interferon-γ from Gadus macrocephalus. Viruses. 14(10):
Kasher, P.R., Jenkinson, E.M., Briolat, V., Gent, D., Morrissey, C., Zeef, L.A., Rice, G.I., Levraud, J.P., Crow, Y.J. (2015) Characterization of samhd1 Morphant Zebrafish Recapitulates Features of the Human Type I Interferonopathy Aicardi-Goutières Syndrome. Journal of immunology (Baltimore, Md. : 1950). 194(6):2819-25
Lai, Y., Liang, M., Hu, ., Zeng, Z., Lin, H., Yi, G., Li, M., Liu, Z. (2018) RNF135 is a positive regulator of IFN expression and involved in RIG-I signaling pathway by targeting RIG-I. Fish & shellfish immunology. 86:474-479
Lee, S.H., Peng, K.C., Lee, L.H., Pan, C.Y., Hour, A.L., Her, G.M., Hui, C.F., and Chen, J.Y. (2013) Characterization of tilapia (Oreochromis niloticus) viperin expression, and inhibition of bacterial growth and modulation of immune-related gene expression by electrotransfer of viperin DNA into zebrafish muscle. Veterinary Immunology and Immunopathology. 151(3-4):217-228
Lefkopoulos, S., Polyzou, A., Derecka, M., Bergo, V., Clapes, T., Cauchy, P., Jerez-Longres, C., Onishi-Seebacher, M., Yin, N., Martagon-Calderón, N.A., Potts, K.S., Klaeylé, L., Liu, F., Bowman, T.V., Jenuwein, T., Mione, M.C., Trompouki, E. (2020) Repetitive Elements Trigger RIG-I-like Receptor Signaling that Regulates the Emergence of Hematopoietic Stem and Progenitor Cells. Immunity. 53:934-951.e9
Li, C., Zhong, S., Ni, S., Liu, Z., Zhang, S., Ji, G. (2021) Zebrafish Ism1 is a novel antiviral factor that positively regulates antiviral immune responses. Developmental and comparative immunology. 125:104210
Li, S., Lu, L.F., Wang, Z.X., Chen, D.D., Zhang, Y.A. (2016) Fish IRF6 is a positive regulator of IFN expression and involved in both of the MyD88 and TBK1 pathways. Fish & shellfish immunology. 57:262-8
Li, Y., Esain, V., Teng, L., Xu, J., Kwan, W., Frost, I.M., Yzaguirre, A.D., Cai, X., Cortes, M., Maijenburg, M.W., Tober, J., Dzierzak, E., Orkin, S.H., Tan, K., North, T.E., Speck, N.A. (2014) Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production. Genes & Development. 28(23):2597-612
Li, Y.L., Gong, X.Y., Qu, Z.L., Zhao, X., Dan, C., Sun, H.Y., An, L.L., Gui, J.F., Zhang, Y.B. (2023) Zebrafish HERC7c Acts as an Inhibitor of Fish IFN Response. International Journal of Molecular Sciences. 24(5):
Li, Z., Xu, X., Huang, L., Wu, J., Lu, Q., Xiang, Z., Liao, J., Weng, S., Yu, X., and He, J. (2010) Administration of recombinant IFN1 protects zebrafish (Danio rerio) from ISKNV infection. Fish & shellfish immunology. 29(3):399-406
Liang, H., Li, Y., Li, M., Zhou, W., Chen, J., Zhang, Z., Yang, Y., Ran, C., Zhou, Z. (2022) The effect and underlying mechanism of yeast β-glucan on antiviral resistance of zebrafish against spring viremia of carp virus infection. Frontiers in immunology. 13:1031962
Liao, Q., Ouyang, G., Zhu, J., Cai, X., Yu, G., Zhou, Z., Liu, X., Wang, J., Xiao, W. (2021) Zebrafish sirt7 Negatively Regulates Antiviral Responses by Attenuating Phosphorylation of irf3 and irf7 Independent of Its Enzymatic Activity. Journal of immunology (Baltimore, Md. : 1950). 207(12):3050-3059
Lin, X., Zhou, Q., Lin, G., Zhao, C., Wen, Z. (2020) Endoderm-Derived Myeloid-like Metaphocytes in Zebrafish Gill Mediate Soluble Antigen-Induced Immunity. Cell Reports. 33:108227
Liu, C., Su, G., Giesy, J.P., Letcher, R.J., Li, G., Agrawal, I., Li, J., Yu, L., Wang, J., Gong, Z. (2016) Acute Exposure to Tris(1,3-dichloro-2-propyl) Phosphate (TDCIPP) Causes Hepatic Inflammation and Leads to Hepatotoxicity in Zebrafish. Scientific Reports. 6:19045
Liu, R., Hu, X., Lü, A., Song, Y., Lian, Z., Sun, J., Sung, Y.Y. (2020) Proteomic Profiling of Zebrafish Challenged by Spring Viremia of Carp Virus Provides Insight into Skin Antiviral Response. Zebrafish. 17:91-103
Liu, S.B., Lu, L.F., Lu, X.B., Li, S., Zhang, Y.A. (2019) Zebrafish FGFR3 is a negative regulator of RLR pathway to decrease IFN expression. Fish & shellfish immunology. 92:224-229
Liu, X., Cai, X., Zhang, D., Xu, C., Xiao, W. (2016) Zebrafish foxo3b Negatively Regulates Antiviral Response through Suppressing the Transactivity of irf3 and irf7. Journal of immunology (Baltimore, Md. : 1950). 197(12):4736-4749
Lu, L.F., Li, S., Lu, X.B., Zhang, Y.A. (2015) Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7. Fish & shellfish immunology. 45(2):574-82
Lu, L.F., Zhang, C., Li, Z.C., Zhou, X.Y., Jiang, J.Y., Chen, D.D., Zhang, Y.A., Xiong, F., Zhou, F., Li, S. (2021) A novel role of Zebrafish TMEM33 in negative regulation of interferon production by two distinct mechanisms. PLoS pathogens. 17:e1009317
Lu, L.F., Zhou, X.Y., Zhang, C., Li, Z.C., Chen, D.D., Liu, S.B., Li, S. (2019) Zebrafish RPZ5 Degrades the Phosphorylated IRF7 to Repress Interferon Production. Journal of virology. 93(21):
Lu, X., Li, X., He, Q., Gao, J., Gao, Y., Liu, B., and Liu, F. (2013) miR-142-3p regulates the formation and differentiation of hematopoietic stem cells in vertebrates. Cell Research. 23(12):1356-68
Lu, X., Wei, Y., Liu, F. (2015) Direct regulation of p53 by miR-142a-3p mediates the survival of hematopoietic stem and progenitor cells in zebrafish. Cell discovery. 1:15027
M, R., Medina-Gali, ., Belló-Pérez, M., Martínez-López, A., Falcó, A., Ortega-Villaizan, M.M., Encinar, J.A., Novoa, B., Coll, J., Perez, L. (2018) Chromatin immunoprecipitation and high throughput sequencing of SVCV-infected zebrafish reveals novel epigenetic histone methylation patterns involved in antiviral immune response. Fish & shellfish immunology. 82:514-521
Madakashira, B., Corbett, L., Zhang, C., Paoli, P., Casement, J.W., Mann, J., Sadler, K.C., Mann, D.A. (2017) Variant Histone H2afv Reprograms DNA Methylation During Early Zebrafish Development. Epigenetics. 12(9):811-824
Madushani, K.P., Shanaka, K.A.S.N., Jung, S., Kim, M.J., Lee, J. (2023) Ablation of myd88 alters the immune gene expression and immune cell recruitment during VHSV infection in zebrafish. Fish & shellfish immunology. 141:109006
Magnani, E., Macchi, F., Madakashira, B.P., Zhang, C., Alaydaroos, F., Sadler, K.C. (2021) uhrf1 and dnmt1 Loss Induces an Immune Response in Zebrafish Livers Due to Viral Mimicry by Transposable Elements. Frontiers in immunology. 12:627926
Matsui, H., Ito, J., Matsui, N., Uechi, T., Onodera, O., Kakita, A. (2021) Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease. Nature communications. 12:3101
Palha, N., Guivel-Benhassine, F., Briolat, V., Lutfalla, G., Sourisseau, M., Ellett, F., Wang, C.H., Lieschke, G.J., Herbomel, P., Schwartz, O., and Levraud, J.P. (2013) Real-time whole-body visualization of chikungunya virus infection and host interferon response in zebrafish. PLoS pathogens. 9(9):e1003619
Qu, Z.L., Gong, X.Y., An, L.L., Sun, H.Y., Guo, W.H., Luan, H.Y., Wu, M.Y., Dan, C., Gui, J.F., Zhang, Y.B. (2024) Genome editing of FTR42 improves zebrafish survival against virus infection by enhancing IFN immunity. iScience. 27:109497109497
Rajshekar, S., Yao, J., Arnold, P.K., Payne, S.G., Zhang, Y., Bowman, T.V., Schmitz, R.J., Edwards, J.R., Goll, M. (2018) Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome. eLIFE. 7:
Rakus, K., Mojzesz, M., Widziolek, M., Pooranachandran, N., Teitge, F., Surachetpong, W., Chadzinska, M., Steinhagen, D., Adamek, M. (2020) Antiviral response of adult zebrafish (Danio rerio) during tilapia lake virus (TiLV) infection. Fish & shellfish immunology. 101:1-8
Rey, S., Moiche, V., Boltaña, S., Teles, M., MacKenzie, S. (2017) Behavioural fever in zebrafish larvae. Developmental and comparative immunology. 67:287-292
Sellaththurai, S., Jung, S., Kim, M.J., Nadarajapillai, K., Ganeshalingam, S., Jeong, J.B., Lee, J. (2023) CRISPR/Cas9-Induced Knockout of Sting Increases Susceptibility of Zebrafish to Bacterial Infection. Biomolecules. 13(2):
Serifi, I., Tzima, E., Bardouki, H., Lampri, E., Papamarcaki, T. (2019) Effects of the Essential Oil from Pistacia lentiscus Var. chia on the Lateral Line System and the Gene Expression Profile of Zebrafish (Danio rerio). Molecules. 24(21):
Shan, S., Qi, C., Zhu, Y., Li, H., An, L., Yang, G. (2016) Expression Profile of Carp IFN Correlate with the Up-regulation of Interferon Regulatory Factor-1 (IRF-1) in Vivo and in Vitro: the Pivotal Molecules in Antiviral Defense. Fish & shellfish immunology. 52:94-102
Shan, Y., Zhang, Y., Zhuo, X., Li, X., Peng, J., Fang, W. (2016) Matrix metalloproteinase-9 plays a role in protecting zebrafish from lethal infection with Listeria monocytogenes by enhacing macrophage migration. Fish & shellfish immunology. 54:179-87
Shi, J., Zhang, Y.B., Zhang, J.S., and Gui, J.F. (2013) Expression regulation of zebrafish interferon regulatory factor 9 by promoter analysis. Developmental and comparative immunology. 41(4):534-543
Stein, C., Caccamo, M., Laird, G., and Leptin, M. (2007) Conservation and divergence of gene families encoding components of innate immune response systems in the zebrafish. Genome biology. 8(11):R251
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
Sun, F., Zhang, Y.B., Liu, T.K., Shi, J., Wang, B., and Gui, J.F. (2011) Fish MITA Serves as a Mediator for Distinct Fish IFN Gene Activation Dependent on IRF3 or IRF7. Journal of immunology (Baltimore, Md. : 1950). 187(5):2531-9
Thwaite, R., Ji, J., Torrealba, D., Coll, J., Sabés, M., Villaverde, A., Roher, N. (2018) Protein Nanoparticles Made of Recombinant Viral Antigens: A Promising Biomaterial for Oral Delivery of Fish Prophylactics. Frontiers in immunology. 9:1652
Veneman, W.J., Stockhammer, O.W., de Boer, L., Zaat, S.A., Meijer, A.H., and Spaink, H.P. (2013) A zebrafish high throughput screening system used for Staphylococcus epidermidis infection marker discovery. BMC Genomics. 14(1):255
Wang, L., Li, Y., Liu, Y., Zuo, L., Li, Y., Wu, S., Huang, R. (2019) Salmonella spv locus affects type I interferon response and the chemotaxis of neutrophils via suppressing autophagy. Fish & shellfish immunology. 87:721-729
Wang, W.L., Liu, W., Gong, H.Y., Hong, J.R., Lin, C.C., and Wu, J.L. (2011) Activation of cytokine expression occurs through the tnfα/nf-κb-mediated pathway in birnavirus-infected cells. Fish & shellfish immunology. 31(1):10-21
Weiss, A., D'Amata, C., Pearson, B.J., Hayes, M.N. (2024) A syngeneic spontaneous zebrafish model of tp53-deficient, EGFR^vIII, and PI3KCA^H1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo. eLIFE. 13:
Widziolek, M., Janik, K., Mojzesz, M., Pooranachandran, N., Adamek, M., Pecio, A., Surachetpong, W., Levraud, J.P., Boudinot, P., Chadzinska, M., Rakus, K. (2020) Type I interferon-dependent response of zebrafish larvae during tilapia lake virus (TiLV) infection. Developmental and comparative immunology. 116:103936
Wu, J., Li, J., Chen, K., Liu, G., Zhou, Y., Chen, W., Zhu, X., Ni, T.T., Zhang, B., Jin, D., Li, D., Kang, L., Wu, Y., Zhu, P., Xie, P., Zhong, T.P. (2023) Atf7ip and Setdb1 interaction orchestrates the hematopoietic stem and progenitor cell state with diverse lineage differentiation. Proceedings of the National Academy of Sciences of the United States of America. 120:e2209062120e2209062120
Xiang, Z., Dong, C., Qi, L., Chen, W., Huang, L., Li, Z., Xia, Q., Liu, D., Huang, M., Weng, S., and He, J. (2010) Characteristics of the interferon regulatory factor pairs zfIRF5/7 and their stimulation expression by ISKNV Infection in zebrafish (Danio rerio). Developmental and comparative immunology. 34(12):1263-1273
Xiong, F., Cao, L., Wu, X.M., Chang, M.X. (2020) The function of zebrafish gpbar1 in antiviral response and lipid metabolism. Developmental and comparative immunology. 116:103955
Xiong, G., Zou, L., Deng, Y., Meng, Y., Liao, X., Lu, H. (2018) Clethodim exposure induces developmental immunotoxicity and neurobehavioral dysfunction in zebrafish embryos. Fish & shellfish immunology. 86:549-558
Xiong, S.T., Ying, Y.R., Long, Z., Li, J.H., Zhang, Y.B., Xiao, T.Y., Zhao, X. (2023) Zebrafish MARCH7 negatively regulates IFN antiviral response by degrading TBK1. International journal of biological macromolecules. 240:124384
Yu, G., Li, X., Zhou, Z., Tang, J., Wang, J., Liu, X., Fan, S., Ouyang, G., Xiao, W. (2020) Zebrafish phd3 Negatively Regulates Antiviral Responses via Suppression of Irf7 Transactivity Independent of Its Prolyl Hydroxylase Activity. Journal of immunology (Baltimore, Md. : 1950). 205(4):1135-1146
Yu, G.Q., Chen, M.J., Wang, Y.J., Liu, Y.Q., Zuo, M.Z., Zhang, Z.H., Li, G.X., Liu, B.Z., Li, M. (2023) Zebrafish spop promotes ubiquitination and degradation of mavs to suppress antiviral response via the lysosomal pathway. International journal of biological macromolecules. 256(Pt 2):128451
Zhang, C., Lu, L.F., Li, Z.C., Han, K.J., Wang, X.L., Chen, D.D., Xiong, F., Li, X.Y., Zhou, L., Ge, F., Li, S. (2023) Zebrafish MAP2K7 Simultaneously Enhances Host IRF7 Stability and Degrades Spring Viremia of Carp Virus P Protein via Ubiquitination Pathway. Journal of virology. 97(7):e0053223
Zhang, Q., Meng, F., Chen, S., Plouffe, S.W., Wu, S., Liu, S., Li, X., Zhou, R., Wang, J., Zhao, B., Liu, J., Qin, J., Zou, J., Feng, X.H., Guan, K.L., Xu, P. (2017) Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade. Nature cell biology. 19(4):362-374
Zhang, Q.M., Zhao, X., Li, Z., Wu, M., Gui, J.F., Zhang, Y.B. (2017) Alternative Splicing Transcripts of Zebrafish LGP2 Gene Differentially Contribute to IFN Antiviral Response. Journal of immunology (Baltimore, Md. : 1950). 200(2):688-703
Zhao, X., Dan, C., Gong, X.Y., Li, Y.L., Qu, Z.L., Sun, H.Y., An, L.L., Guo, W.H., Gui, J.F., Zhang, Y.B. (2022) Zebrafish MARCH8 downregulates fish IFN response by targeting MITA and TBK1 for protein degradation. Developmental and comparative immunology. 135:104485
Zhao, X., Gong, X.Y., Li, Y.L., Dan, C., Gui, J.F., Zhang, Y.B. (2020) Characterization of DNA Binding and Nuclear Retention Identifies Zebrafish IRF11 as a Positive Regulator of IFN Antiviral Response. Journal of immunology (Baltimore, Md. : 1950). 205(1):237-250
Zhao, X., Huang, W., Shi, Y., Guo, J., Xiao, H., Ji, N., Feng, J., Dang, H., Zou, J. (2022) PLAAT1 inhibits type I interferon response via degradation of IRF3 and IRF7 in Zebrafish. Frontiers in immunology. 13:979919
Zheng, M., Lu, J., Zhao, D. (2017) Effects of starch-coating of magnetite nanoparticles on cellular uptake, toxicity and gene expression profiles in adult zebrafish. The Science of the total environment. 622-623:930-941
Zhong, S., Li, H., Wang, Y.S., Wang, Y., Ji, G., Li, H.Y., Zhang, S., Liu, Z. (2021) Bmp8a is an essential positive regulator of antiviral immunity in zebrafish. Communications biology. 4:318
Zhou, W., Pal, A.S., Hsu, A.Y., Gurol, T., Zhu, X., Wirbisky-Hershberger, S.E., Freeman, J.L., Kasinski, A.L., Deng, Q. (2018) MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation. Cell Reports. 22:1810-1823
Zhu, J., Liu, X., Cai, X., Ouyang, G., Fan, S., Wang, J., Xiao, W. (2020) Zebrafish prmt7 negatively regulates antiviral responses by suppressing the retinoic acid-inducible gene-I-like receptor signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34:988-1000
Zou, P.F., Chang, M.X., Li, Y., Zhang, S.H., Fu, J.P., Chen, S.N., Nie, P. (2015) Higher antiviral response of RIG-I through enhancing RIG-I/MAVS-mediated signaling by its long insertion variant in zebrafish. Fish & shellfish immunology. 43(1):13-24

Qu, Z.L., Gong, X.Y., An, L.L., Sun, H.Y., Guo, W.H., Luan, H.Y., Wu, M.Y., Dan, C., Gui, J.F., Zhang, Y.B. (2024) Genome editing of FTR42 improves zebrafish survival against virus infection by enhancing IFN immunity. iScience. 27:109497109497
Weiss, A., D'Amata, C., Pearson, B.J., Hayes, M.N. (2024) A syngeneic spontaneous zebrafish model of tp53-deficient, EGFR^vIII, and PI3KCA^H1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo. eLIFE. 13:
Li, Y.L., Gong, X.Y., Qu, Z.L., Zhao, X., Dan, C., Sun, H.Y., An, L.L., Gui, J.F., Zhang, Y.B. (2023) Zebrafish HERC7c Acts as an Inhibitor of Fish IFN Response. International Journal of Molecular Sciences. 24(5):
Madushani, K.P., Shanaka, K.A.S.N., Jung, S., Kim, M.J., Lee, J. (2023) Ablation of myd88 alters the immune gene expression and immune cell recruitment during VHSV infection in zebrafish. Fish & shellfish immunology. 141:109006
Sellaththurai, S., Jung, S., Kim, M.J., Nadarajapillai, K., Ganeshalingam, S., Jeong, J.B., Lee, J. (2023) CRISPR/Cas9-Induced Knockout of Sting Increases Susceptibility of Zebrafish to Bacterial Infection. Biomolecules. 13(2):
Wu, J., Li, J., Chen, K., Liu, G., Zhou, Y., Chen, W., Zhu, X., Ni, T.T., Zhang, B., Jin, D., Li, D., Kang, L., Wu, Y., Zhu, P., Xie, P., Zhong, T.P. (2023) Atf7ip and Setdb1 interaction orchestrates the hematopoietic stem and progenitor cell state with diverse lineage differentiation. Proceedings of the National Academy of Sciences of the United States of America. 120:e2209062120e2209062120
Xiong, S.T., Ying, Y.R., Long, Z., Li, J.H., Zhang, Y.B., Xiao, T.Y., Zhao, X. (2023) Zebrafish MARCH7 negatively regulates IFN antiviral response by degrading TBK1. International journal of biological macromolecules. 240:124384
Yu, G.Q., Chen, M.J., Wang, Y.J., Liu, Y.Q., Zuo, M.Z., Zhang, Z.H., Li, G.X., Liu, B.Z., Li, M. (2023) Zebrafish spop promotes ubiquitination and degradation of mavs to suppress antiviral response via the lysosomal pathway. International journal of biological macromolecules. 256(Pt 2):128451
Zhang, C., Lu, L.F., Li, Z.C., Han, K.J., Wang, X.L., Chen, D.D., Xiong, F., Li, X.Y., Zhou, L., Ge, F., Li, S. (2023) Zebrafish MAP2K7 Simultaneously Enhances Host IRF7 Stability and Degrades Spring Viremia of Carp Virus P Protein via Ubiquitination Pathway. Journal of virology. 97(7):e0053223
An, L.L., Zhao, X., Gong, X.Y., Li, Y.L., Qu, Z.L., Sun, H.Y., Guo, W.H., Dan, C., Gui, J.F., Zhang, Y.B. (2022) Promoter Binding and Nuclear Retention Features of Zebrafish IRF Family Members in IFN Response. Frontiers in immunology. 13:861262
Gong, X.Y., Zhang, Q.M., Zhao, X., Li, Y.L., Qu, Z.L., Li, Z., Dan, C., Gui, J.F., Zhang, Y.B. (2022) LGP2 is essential for zebrafish survival through dual regulation of IFN antiviral response. iScience. 25:104821
Jiang, J., Gu, J., Zhan, A., Mao, M., Liu, Y., Wang, H., Mao, Y. (2022) Cloning, Exogenous Expression and Function Analysis of Interferon-γ from Gadus macrocephalus. Viruses. 14(10):
Liang, H., Li, Y., Li, M., Zhou, W., Chen, J., Zhang, Z., Yang, Y., Ran, C., Zhou, Z. (2022) The effect and underlying mechanism of yeast β-glucan on antiviral resistance of zebrafish against spring viremia of carp virus infection. Frontiers in immunology. 13:1031962
Zhao, X., Dan, C., Gong, X.Y., Li, Y.L., Qu, Z.L., Sun, H.Y., An, L.L., Guo, W.H., Gui, J.F., Zhang, Y.B. (2022) Zebrafish MARCH8 downregulates fish IFN response by targeting MITA and TBK1 for protein degradation. Developmental and comparative immunology. 135:104485
Zhao, X., Huang, W., Shi, Y., Guo, J., Xiao, H., Ji, N., Feng, J., Dang, H., Zou, J. (2022) PLAAT1 inhibits type I interferon response via degradation of IRF3 and IRF7 in Zebrafish. Frontiers in immunology. 13:979919
Chen, S.N., Gan, Z., Nie, P. (2021) Retroposition of the Long Transcript from Multiexon IFN-β Homologs in Ancestry Vertebrate Gave Rise to the Proximal Transcription Elements of Intronless IFN-β Promoter in Humans. Journal of immunology (Baltimore, Md. : 1950). 207(10):2512-2520
Hu, S.Q., Xu, H.M., Qian, F., Chen, C.S., Wang, X., Liu, D., Cheng, L. (2021) Interferon regulatory factor-7 is required for hair cell development during zebrafish embryogenesis. Developmental Neurobiology. 82(1):88-97
Li, C., Zhong, S., Ni, S., Liu, Z., Zhang, S., Ji, G. (2021) Zebrafish Ism1 is a novel antiviral factor that positively regulates antiviral immune responses. Developmental and comparative immunology. 125:104210
Liao, Q., Ouyang, G., Zhu, J., Cai, X., Yu, G., Zhou, Z., Liu, X., Wang, J., Xiao, W. (2021) Zebrafish sirt7 Negatively Regulates Antiviral Responses by Attenuating Phosphorylation of irf3 and irf7 Independent of Its Enzymatic Activity. Journal of immunology (Baltimore, Md. : 1950). 207(12):3050-3059
Lu, L.F., Zhang, C., Li, Z.C., Zhou, X.Y., Jiang, J.Y., Chen, D.D., Zhang, Y.A., Xiong, F., Zhou, F., Li, S. (2021) A novel role of Zebrafish TMEM33 in negative regulation of interferon production by two distinct mechanisms. PLoS pathogens. 17:e1009317
Magnani, E., Macchi, F., Madakashira, B.P., Zhang, C., Alaydaroos, F., Sadler, K.C. (2021) uhrf1 and dnmt1 Loss Induces an Immune Response in Zebrafish Livers Due to Viral Mimicry by Transposable Elements. Frontiers in immunology. 12:627926
Matsui, H., Ito, J., Matsui, N., Uechi, T., Onodera, O., Kakita, A. (2021) Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease. Nature communications. 12:3101
Zhong, S., Li, H., Wang, Y.S., Wang, Y., Ji, G., Li, H.Y., Zhang, S., Liu, Z. (2021) Bmp8a is an essential positive regulator of antiviral immunity in zebrafish. Communications biology. 4:318
Chen, B., Li, C., Yao, J., Shi, L., Liu, W., Wang, F., Huo, S., Zhang, Y., Lu, Y., Ashraf, U., Ye, J., Liu, X. (2020) Zebrafish NIK Mediates IFN Induction by Regulating Activation of IRF3 and NF-κB. Journal of immunology (Baltimore, Md. : 1950). 204(7):1881-1891
Chen, C., Lu, M., Lin, S., Qin, W. (2020) The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond-Blackfan anemia. Cell Death & Disease. 11:135
Chen, S., Gong, Z., Letcher, R.J., Liu, C. (2020) Promotion effect of liver tumor progression in male kras transgenic zebrafish induced by tris (1, 3-dichloro-2-propyl) phosphate. Ecotoxicology and environmental safety. 191:110220
Chen, S., Liu, S., Wang, J., Wu, Q., Wang, A., Guan, H., Zhang, Q., Zhang, D., Wang, X., Song, H., Qin, J., Zou, J., Jiang, Z., Ouyang, S., Feng, X.H., Liang, T., Xu, P. (2020) TBK1-Mediated DRP1 Targeting Confers Nucleic Acid Sensing to Reprogram Mitochondrial Dynamics and Physiology. Molecular Cell. 80:810-827.e7
Demin, K.A., Lakstygal, A.M., Krotova, N.A., Masharsky, A., Tagawa, N., Chernysh, M.V., Ilyin, N.P., Taranov, A.S., Galstyan, D.S., Derzhavina, K.A., Levchenko, N.A., Kolesnikova, T.O., Mor, M.S., Vasyutina, M.L., Efimova, E.V., Katolikova, N., Prjibelski, A.D., Gainetdinov, R.R., de Abreu, M.S., Amstislavskaya, T.G., Strekalova, T., Kalueff, A.V. (2020) Understanding complex dynamics of behavioral, neurochemical and transcriptomic changes induced by prolonged chronic unpredictable stress in zebrafish. Scientific Reports. 10:19981
Lefkopoulos, S., Polyzou, A., Derecka, M., Bergo, V., Clapes, T., Cauchy, P., Jerez-Longres, C., Onishi-Seebacher, M., Yin, N., Martagon-Calderón, N.A., Potts, K.S., Klaeylé, L., Liu, F., Bowman, T.V., Jenuwein, T., Mione, M.C., Trompouki, E. (2020) Repetitive Elements Trigger RIG-I-like Receptor Signaling that Regulates the Emergence of Hematopoietic Stem and Progenitor Cells. Immunity. 53:934-951.e9
Lin, X., Zhou, Q., Lin, G., Zhao, C., Wen, Z. (2020) Endoderm-Derived Myeloid-like Metaphocytes in Zebrafish Gill Mediate Soluble Antigen-Induced Immunity. Cell Reports. 33:108227
Liu, R., Hu, X., Lü, A., Song, Y., Lian, Z., Sun, J., Sung, Y.Y. (2020) Proteomic Profiling of Zebrafish Challenged by Spring Viremia of Carp Virus Provides Insight into Skin Antiviral Response. Zebrafish. 17:91-103
Rakus, K., Mojzesz, M., Widziolek, M., Pooranachandran, N., Teitge, F., Surachetpong, W., Chadzinska, M., Steinhagen, D., Adamek, M. (2020) Antiviral response of adult zebrafish (Danio rerio) during tilapia lake virus (TiLV) infection. Fish & shellfish immunology. 101:1-8
Widziolek, M., Janik, K., Mojzesz, M., Pooranachandran, N., Adamek, M., Pecio, A., Surachetpong, W., Levraud, J.P., Boudinot, P., Chadzinska, M., Rakus, K. (2020) Type I interferon-dependent response of zebrafish larvae during tilapia lake virus (TiLV) infection. Developmental and comparative immunology. 116:103936
Xiong, F., Cao, L., Wu, X.M., Chang, M.X. (2020) The function of zebrafish gpbar1 in antiviral response and lipid metabolism. Developmental and comparative immunology. 116:103955
Yu, G., Li, X., Zhou, Z., Tang, J., Wang, J., Liu, X., Fan, S., Ouyang, G., Xiao, W. (2020) Zebrafish phd3 Negatively Regulates Antiviral Responses via Suppression of Irf7 Transactivity Independent of Its Prolyl Hydroxylase Activity. Journal of immunology (Baltimore, Md. : 1950). 205(4):1135-1146
Zhao, X., Gong, X.Y., Li, Y.L., Dan, C., Gui, J.F., Zhang, Y.B. (2020) Characterization of DNA Binding and Nuclear Retention Identifies Zebrafish IRF11 as a Positive Regulator of IFN Antiviral Response. Journal of immunology (Baltimore, Md. : 1950). 205(1):237-250
Zhu, J., Liu, X., Cai, X., Ouyang, G., Fan, S., Wang, J., Xiao, W. (2020) Zebrafish prmt7 negatively regulates antiviral responses by suppressing the retinoic acid-inducible gene-I-like receptor signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34:988-1000
Chen, S., Dang, Y., Gong, Z., Letcher, R.J., Liu, C. (2019) Progression of liver tumor was promoted by tris(1,3-dichloro-2-propyl) phosphate through the induction of inflammatory responses in kras^V12 transgenic zebrafish. Environmental pollution (Barking, Essex : 1987). 255:113315
Guo, J., Wu, P., Cao, J., Luo, Y., Chen, J., Wang, G., Guo, W., Wang, T., He, X. (2019) The PFOS disturbed immunomodulatory functions via nuclear Factor-κB signaling in liver of zebrafish (Danio rerio). Fish & shellfish immunology. 91:87-98
Liu, S.B., Lu, L.F., Lu, X.B., Li, S., Zhang, Y.A. (2019) Zebrafish FGFR3 is a negative regulator of RLR pathway to decrease IFN expression. Fish & shellfish immunology. 92:224-229
Lu, L.F., Zhou, X.Y., Zhang, C., Li, Z.C., Chen, D.D., Liu, S.B., Li, S. (2019) Zebrafish RPZ5 Degrades the Phosphorylated IRF7 to Repress Interferon Production. Journal of virology. 93(21):
Serifi, I., Tzima, E., Bardouki, H., Lampri, E., Papamarcaki, T. (2019) Effects of the Essential Oil from Pistacia lentiscus Var. chia on the Lateral Line System and the Gene Expression Profile of Zebrafish (Danio rerio). Molecules. 24(21):
Wang, L., Li, Y., Liu, Y., Zuo, L., Li, Y., Wu, S., Huang, R. (2019) Salmonella spv locus affects type I interferon response and the chemotaxis of neutrophils via suppressing autophagy. Fish & shellfish immunology. 87:721-729
Danilova, N., Wilkes, M., Bibikova, E., Youn, M.Y., Sakamoto, K.M., Lin, S. (2018) Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. Scientific Reports. 8:5165
Lai, Y., Liang, M., Hu, ., Zeng, Z., Lin, H., Yi, G., Li, M., Liu, Z. (2018) RNF135 is a positive regulator of IFN expression and involved in RIG-I signaling pathway by targeting RIG-I. Fish & shellfish immunology. 86:474-479
M, R., Medina-Gali, ., Belló-Pérez, M., Martínez-López, A., Falcó, A., Ortega-Villaizan, M.M., Encinar, J.A., Novoa, B., Coll, J., Perez, L. (2018) Chromatin immunoprecipitation and high throughput sequencing of SVCV-infected zebrafish reveals novel epigenetic histone methylation patterns involved in antiviral immune response. Fish & shellfish immunology. 82:514-521
Rajshekar, S., Yao, J., Arnold, P.K., Payne, S.G., Zhang, Y., Bowman, T.V., Schmitz, R.J., Edwards, J.R., Goll, M. (2018) Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome. eLIFE. 7:
Thwaite, R., Ji, J., Torrealba, D., Coll, J., Sabés, M., Villaverde, A., Roher, N. (2018) Protein Nanoparticles Made of Recombinant Viral Antigens: A Promising Biomaterial for Oral Delivery of Fish Prophylactics. Frontiers in immunology. 9:1652
Xiong, G., Zou, L., Deng, Y., Meng, Y., Liao, X., Lu, H. (2018) Clethodim exposure induces developmental immunotoxicity and neurobehavioral dysfunction in zebrafish embryos. Fish & shellfish immunology. 86:549-558
Zhou, W., Pal, A.S., Hsu, A.Y., Gurol, T., Zhu, X., Wirbisky-Hershberger, S.E., Freeman, J.L., Kasinski, A.L., Deng, Q. (2018) MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation. Cell Reports. 22:1810-1823
Chernyavskaya, Y., Mudbhary, R., Tokarz, D., Jacob, V., Gopinath, S., Zhang, C., Sun, X., Wang, S., Magnani, E., Madakashira, B.P., Yoder, J.A., Hoshida, Y., Sadler, K.C. (2017) Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development (Cambridge, England). 144(16):2925-2939
Madakashira, B., Corbett, L., Zhang, C., Paoli, P., Casement, J.W., Mann, J., Sadler, K.C., Mann, D.A. (2017) Variant Histone H2afv Reprograms DNA Methylation During Early Zebrafish Development. Epigenetics. 12(9):811-824
Rey, S., Moiche, V., Boltaña, S., Teles, M., MacKenzie, S. (2017) Behavioural fever in zebrafish larvae. Developmental and comparative immunology. 67:287-292
Zhang, Q., Meng, F., Chen, S., Plouffe, S.W., Wu, S., Liu, S., Li, X., Zhou, R., Wang, J., Zhao, B., Liu, J., Qin, J., Zou, J., Feng, X.H., Guan, K.L., Xu, P. (2017) Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade. Nature cell biology. 19(4):362-374
Zhang, Q.M., Zhao, X., Li, Z., Wu, M., Gui, J.F., Zhang, Y.B. (2017) Alternative Splicing Transcripts of Zebrafish LGP2 Gene Differentially Contribute to IFN Antiviral Response. Journal of immunology (Baltimore, Md. : 1950). 200(2):688-703
Zheng, M., Lu, J., Zhao, D. (2017) Effects of starch-coating of magnetite nanoparticles on cellular uptake, toxicity and gene expression profiles in adult zebrafish. The Science of the total environment. 622-623:930-941
Feng, H., Zhang, Q.M., Zhang, Y.B., Li, Z., Zhang, J., Xiong, Y.W., Wu, M., Gui, J.F. (2016) Zebrafish IRF1, IRF3, and IRF7 Differentially Regulate IFNΦ1 and IFNΦ3 Expression through Assembly of Homo- or Heteroprotein Complexes. Journal of immunology (Baltimore, Md. : 1950). 197(5):1893-904
Li, S., Lu, L.F., Wang, Z.X., Chen, D.D., Zhang, Y.A. (2016) Fish IRF6 is a positive regulator of IFN expression and involved in both of the MyD88 and TBK1 pathways. Fish & shellfish immunology. 57:262-8
Liu, C., Su, G., Giesy, J.P., Letcher, R.J., Li, G., Agrawal, I., Li, J., Yu, L., Wang, J., Gong, Z. (2016) Acute Exposure to Tris(1,3-dichloro-2-propyl) Phosphate (TDCIPP) Causes Hepatic Inflammation and Leads to Hepatotoxicity in Zebrafish. Scientific Reports. 6:19045
Liu, X., Cai, X., Zhang, D., Xu, C., Xiao, W. (2016) Zebrafish foxo3b Negatively Regulates Antiviral Response through Suppressing the Transactivity of irf3 and irf7. Journal of immunology (Baltimore, Md. : 1950). 197(12):4736-4749
Shan, S., Qi, C., Zhu, Y., Li, H., An, L., Yang, G. (2016) Expression Profile of Carp IFN Correlate with the Up-regulation of Interferon Regulatory Factor-1 (IRF-1) in Vivo and in Vitro: the Pivotal Molecules in Antiviral Defense. Fish & shellfish immunology. 52:94-102
Shan, Y., Zhang, Y., Zhuo, X., Li, X., Peng, J., Fang, W. (2016) Matrix metalloproteinase-9 plays a role in protecting zebrafish from lethal infection with Listeria monocytogenes by enhacing macrophage migration. Fish & shellfish immunology. 54:179-87
Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
Feng, H., Zhang, Y., Zhang, Q., Li, Z., Zhang, Q., Gui, J. (2015) Zebrafish IRF1 Regulates IFN Antiviral Response through Binding to IFNϕ1 and IFNϕ3 Promoters Downstream of MyD88 Signaling. Journal of immunology (Baltimore, Md. : 1950). 194(3):1225-38
Kasher, P.R., Jenkinson, E.M., Briolat, V., Gent, D., Morrissey, C., Zeef, L.A., Rice, G.I., Levraud, J.P., Crow, Y.J. (2015) Characterization of samhd1 Morphant Zebrafish Recapitulates Features of the Human Type I Interferonopathy Aicardi-Goutières Syndrome. Journal of immunology (Baltimore, Md. : 1950). 194(6):2819-25
Lu, L.F., Li, S., Lu, X.B., Zhang, Y.A. (2015) Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7. Fish & shellfish immunology. 45(2):574-82
Lu, X., Wei, Y., Liu, F. (2015) Direct regulation of p53 by miR-142a-3p mediates the survival of hematopoietic stem and progenitor cells in zebrafish. Cell discovery. 1:15027
Zou, P.F., Chang, M.X., Li, Y., Zhang, S.H., Fu, J.P., Chen, S.N., Nie, P. (2015) Higher antiviral response of RIG-I through enhancing RIG-I/MAVS-mediated signaling by its long insertion variant in zebrafish. Fish & shellfish immunology. 43(1):13-24
Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41
Li, Y., Esain, V., Teng, L., Xu, J., Kwan, W., Frost, I.M., Yzaguirre, A.D., Cai, X., Cortes, M., Maijenburg, M.W., Tober, J., Dzierzak, E., Orkin, S.H., Tan, K., North, T.E., Speck, N.A. (2014) Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production. Genes & Development. 28(23):2597-612
Boltaña, S., Rey, S., Roher, N., Vargas, R., Huerta, M., Huntingford, F.A., Goetzm, F.W., Moore, J., Garcia-Valtanen, P., Estepa, A., and Mackenzie, S. (2013) Behavioural fever is a synergic signal amplifying the innate immune response. Proceedings. Biological sciences. 280(1766):20131381
Lee, S.H., Peng, K.C., Lee, L.H., Pan, C.Y., Hour, A.L., Her, G.M., Hui, C.F., and Chen, J.Y. (2013) Characterization of tilapia (Oreochromis niloticus) viperin expression, and inhibition of bacterial growth and modulation of immune-related gene expression by electrotransfer of viperin DNA into zebrafish muscle. Veterinary Immunology and Immunopathology. 151(3-4):217-228
Lu, X., Li, X., He, Q., Gao, J., Gao, Y., Liu, B., and Liu, F. (2013) miR-142-3p regulates the formation and differentiation of hematopoietic stem cells in vertebrates. Cell Research. 23(12):1356-68
Palha, N., Guivel-Benhassine, F., Briolat, V., Lutfalla, G., Sourisseau, M., Ellett, F., Wang, C.H., Lieschke, G.J., Herbomel, P., Schwartz, O., and Levraud, J.P. (2013) Real-time whole-body visualization of chikungunya virus infection and host interferon response in zebrafish. PLoS pathogens. 9(9):e1003619
Shi, J., Zhang, Y.B., Zhang, J.S., and Gui, J.F. (2013) Expression regulation of zebrafish interferon regulatory factor 9 by promoter analysis. Developmental and comparative immunology. 41(4):534-543
Veneman, W.J., Stockhammer, O.W., de Boer, L., Zaat, S.A., Meijer, A.H., and Spaink, H.P. (2013) A zebrafish high throughput screening system used for Staphylococcus epidermidis infection marker discovery. BMC Genomics. 14(1):255
Cui, H., Yan, Y., Wei, J., Huang, X., Huang, Y., Ouyang, Z., and Qin, Q. (2011) Identification and functional characterization of an interferon regulatory factor 7-like (IRF7-like) gene from orange-spotted grouper, Epinephelus coioides. Developmental and comparative immunology. 35(6):672-684
Sun, F., Zhang, Y.B., Liu, T.K., Shi, J., Wang, B., and Gui, J.F. (2011) Fish MITA Serves as a Mediator for Distinct Fish IFN Gene Activation Dependent on IRF3 or IRF7. Journal of immunology (Baltimore, Md. : 1950). 187(5):2531-9
Wang, W.L., Liu, W., Gong, H.Y., Hong, J.R., Lin, C.C., and Wu, J.L. (2011) Activation of cytokine expression occurs through the tnfα/nf-κb-mediated pathway in birnavirus-infected cells. Fish & shellfish immunology. 31(1):10-21
Huang, B., Qi, Z.T., Xu, Z., and Nie, P. (2010) Global characterization of interferon regulatory factor (IRF) genes in vertebrates: Glimpse of the diversification in evolution. BMC immunology. 11:22
Li, Z., Xu, X., Huang, L., Wu, J., Lu, Q., Xiang, Z., Liao, J., Weng, S., Yu, X., and He, J. (2010) Administration of recombinant IFN1 protects zebrafish (Danio rerio) from ISKNV infection. Fish & shellfish immunology. 29(3):399-406
Xiang, Z., Dong, C., Qi, L., Chen, W., Huang, L., Li, Z., Xia, Q., Liu, D., Huang, M., Weng, S., and He, J. (2010) Characteristics of the interferon regulatory factor pairs zfIRF5/7 and their stimulation expression by ISKNV Infection in zebrafish (Danio rerio). Developmental and comparative immunology. 34(12):1263-1273
Stein, C., Caccamo, M., Laird, G., and Leptin, M. (2007) Conservation and divergence of gene families encoding components of innate immune response systems in the zebrafish. Genome biology. 8(11):R251
Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (18):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.

Varshney, G.K., Zhang, S., Burgess, S.M., ZFIN Staff (2015) Automated Data Load From CRISPRz. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.