ZFIN

ZFIN ID: ZDB-GENE-040108-7

ZFIN ID: ZDB-GENE-040108-7

CITATIONS (66 total)

Gene Name:	xin actin binding repeat containing 2a
Gene Symbol:	xirp2a

Cumplido, N., Arratia, G., Desvignes, T., Muñoz-Sánchez, S., Postlethwait, J.H., Allende, M.L. (2024) Hox genes control homocercal caudal fin development and evolution. Science advances. 10:eadj5991

Miller, B.M., Goessling, W. (2024) The proteasome subunit psmb1 is essential for craniofacial cartilage maturation and morphogenesis. JCI insight. 9(16):

Keseroglu, K., Zinani, O.Q.H., Keskin, S., Seawall, H., Alpay, E.E., Özbudak, E.M. (2023) Stochastic gene expression and environmental stressors trigger variable somite segmentation phenotypes. Nature communications. 14:64976497

Nie, C.H., Wan, S.M., Chen, Y.L., Huysseune, A., Wu, Y.M., Zhou, J.J., Hilsdorf, A.W.S., Wang, W.M., Witten, P.E., Lin, Q., Gao, Z.X. (2022) Single-cell transcriptomes and runx2b^-/- mutants reveal the genetic signatures of intermuscular bone formation in zebrafish. National science review. 9:nwac152nwac152

Simsek, M.F., Chandel, A.S., Saparov, D., Zinani, O.Q.H., Clason, N., Özbudak, E.M. (2022) Periodic inhibition of Erk activity drives sequential somite segmentation. Nature. 613(7942):153-159

Xu, H., Tong, G., Yan, T., Dong, L., Yang, X., Dou, D., Sun, Z., Liu, T., Zheng, X., Yang, J., Sun, X., Zhou, Y., Kuang, Y. (2022) Transcriptomic Analysis Provides Insights to Reveal the bmp6 Function Related to the Development of Intermuscular Bones in Zebrafish. Frontiers in cell and developmental biology. 10:821471

Xue, S., Ly, T.T.N., Vijayakar, R.S., Chen, J., Ng, J., Mathuru, A.S., Magdinier, F., Reversade, B. (2022) HOX epimutations driven by maternal SMCHD1/LRIF1 haploinsufficiency trigger homeotic transformations in genetically wildtype offspring. Nature communications. 13:3583

Zhang, W., Scerbo, P., Delagrange, M., Candat, V., Mayr, V., Vriz, S., Distel, M., Ducos, B., Bensimon, D. (2022) Fgf8 dynamics and critical slowing down may account for the temperature independence of somitogenesis. Communications biology. 5:113

Uriu, K., Liao, B.K., Oates, A.C., Morelli, L.G. (2021) From local resynchronization to global pattern recovery in the zebrafish segmentation clock. eLIFE. 10:

Yamada, K., Maeno, A., Araki, S., Kikuchi, M., Suzuki, M., Ishizaka, M., Satoh, K., Akama, K., Kawabe, Y., Suzuki, K., Kobayashi, D., Hamano, N., Kawamura, A. (2021) An atlas of seven zebrafish hox cluster mutants provides insights into sub/neofunctionalization of vertebrate Hox clusters. Development (Cambridge, England). 148(11):

Prajapati, R.S., Mitter, R., Vezzaro, A., Ish-Horowicz, D. (2020) Greb1 is required for axial elongation and segmentation in vertebrate embryos. Biology Open. 9(2):

Zinani, O.Q.H., Keseroğlu, K., Ay, A., Özbudak, E.M. (2020) Pairing of segmentation clock genes drives robust pattern formation. Nature. 589(7842):431-436

Ban, H., Yokota, D., Otosaka, S., Kikuchi, M., Kinoshita, H., Fujino, Y., Yabe, T., Ovara, H., Izuka, A., Akama, K., Yamasu, K., Takada, S., Kawamura, A. (2019) Transcriptional autoregulation of zebrafish tbx6 is required for somite segmentation. Development (Cambridge, England). 146(18):

Dai, W., Sandoval, I.T., Cai, S., Smith, K.A., Delacruz, R.G.C., Boyd, K.A., Mills, J.J., Jones, D.A., Cichewicz, R.H. (2019) Cholinesterase Inhibitory Arisugacins L-Q from a Penicillium sp. Isolate Obtained through a Citizen Science Initiative and Their Activities in a Phenotype-Based Zebrafish Assay. Journal of natural products. 82(9):2627-2637

Kague, E., Hughes, S.M., A Lawrence, E., Cross, S., Martin-Silverstone, E., Hammond, C.L., Hinits, Y. (2019) Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(8):9116-9130

Keskin, S., Simsek, M.F., Vu, H.T., Yang, C., Devoto, S.H., Ay, A., Özbudak, E.M. (2019) Regulatory Network of the Scoliosis-Associated Genes Establishes Rostrocaudal Patterning of Somites in Zebrafish. iScience. 12:247-259

Young, R.M., Hawkins, T.A., Cavodeassi, F., Stickney, H.L., Schwarz, Q., Lawrence, L.M., Wierzbicki, C., Cheng, B.Y., Luo, J., Ambrosio, E.M., Klosner, A., Sealy, I.M., Rowell, J., Trivedi, C.A., Bianco, I.H., Allende, M.L., Busch-Nentwich, E.M., Gestri, G., Wilson, S.W. (2019) Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification. eLIFE. 8:

Kinoshita, H., Ohgane, N., Fujino, Y., Yabe, T., Ovara, H., Yokota, D., Izuka, A., Kage, D., Yamasu, K., Takada, S., Kawamura, A. (2018) Functional roles of the Ripply-mediated suppression of segmentation gene expression at the anterior presomitic mesoderm in zebrafish. Mechanisms of Development. 152:21-31

LLeras Forero, L., Narayanan, R., Huitema, L.F.A., VanBergen, M., Apschner, A., Peterson-Maduro, J., Logister, I., Valentin, G., Morelli, L.G., Oates, A., Schulte-Merker, S. (2018) Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock. eLIFE. 7

Pinto, R.A., Almeida-Santos, J., Lourenço, R., Saúde, L. (2018) Identification of Dmrt2a downstream genes during zebrafish early development using a timely controlled approach. BMC Developmental Biology. 18:14

Simsek, M.F., Özbudak, E.M. (2018) Spatial Fold Change of FGF Signaling Encodes Positional Information for Segmental Determination in Zebrafish. Cell Reports. 24:66-78.e8

Sánchez-Iranzo, H., Galardi-Castilla, M., Minguillón, C., Sanz-Morejón, A., González-Rosa, J.M., Felker, A., Ernst, A., Guzmán-Martínez, G., Mosimann, C., Mercader, N. (2018) Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration. Nature communications. 9:428

McGurk, P.D., Swartz, M.E., Chen, J.W., Galloway, J.L., Eberhart, J.K. (2017) In vivo zebrafish morphogenesis shows Cyp26b1 promotes tendon condensation and musculoskeletal patterning in the embryonic jaw. PLoS Genetics. 13:e1007112

Morrow, Z.T., Maxwell, A.M., Hoshijima, K., Talbot, J.C., Grunwald, D.J., Amacher, S.L. (2017) tbx6l and tbx16 are redundantly required for posterior paraxial mesoderm formation during zebrafish embryogenesis. Developmental Dynamics : an official publication of the American Association of Anatomists. 246(10):759-769

Richter, S., Schulze, U., Tomançak, P., Oates, A.C. (2017) Small molecule screen in embryonic zebrafish using modular variations to target segmentation. Nature communications. 8:1901

Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37

Liao, B.K., Jörg, D.J., Oates, A.C. (2016) Faster embryonic segmentation through elevated Delta-Notch signalling. Nature communications. 7:11861

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Mikami, S., Nakaura, M., Kawahara, A., Mizoguchi, T., Itoh, M. (2015) Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish. Biology Open. 4(11):1576-82

Chen, J.W., Galloway, J.L. (2014) The development of zebrafish tendon and ligament progenitors. Development (Cambridge, England). 141:2035-45

Hayes, M., Gao, X., Yu, L.X., Paria, N., Henkelman, R.M., Wise, C.A., Ciruna, B. (2014) ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease. Nature communications. 5:4777

Rost, F., Eugster, C., Schröter, C., Oates, A.C., Brusch, L. (2014) Chevron formation of the zebrafish muscle segments. The Journal of experimental biology. 217(Pt 21):3870-82

Soroldoni, D., Jörg, D.J., Morelli, L.G., Richmond, D.L., Schindelin, J., Jülicher, F., Oates, A.C. (2014) Genetic oscillations. A Doppler effect in embryonic pattern formation. Science (New York, N.Y.). 345:222-5

Soza-Ried, C., Oztürk, E., Ish-Horowicz, D., Lewis, J. (2014) Pulses of Notch activation synchronise oscillating somite cells and entrain the zebrafish segmentation clock. Development (Cambridge, England). 141:1780-8

Hanisch, A., Holder, M.V., Choorapoikayil, S., Gajewski, M., Ozbudak, E.M., and Lewis, J. (2013) The elongation rate of RNA polymerase II in zebrafish and its significance in the somite segmentation clock. Development (Cambridge, England). 140(2):444-453

Fior, R., Maxwell, A.A., Ma, T.P., Vezzaro, A., Moens, C.B., Amacher, S.L., Lewis, J., and Saúde, L. (2012) The differentiation and movement of presomitic mesoderm progenitor cells are controlled by Mesogenin 1. Development (Cambridge, England). 139(24):4656-4665

Gomez, G., Lee, J.H., Veldman, M.B., Lu, J., Xiao, X., and Lin, S. (2012) Identification of Vascular and Hematopoietic Genes Downstream of etsrp by Deep Sequencing in Zebrafish. PLoS One. 7(3):e31658

Otten, C., van der Ven, P.F., Lewrenz, I., Paul, S., Steinhagen, A., Busch-Nentwich, E., Eichhorst, J., Wiesner, B., Stemple, D., Strähle, U., Fürst, D.O., and Abdelilah-Seyfried, S. (2012) Xirp proteins mark injured skeletal muscle in zebrafish. PLoS One. 7(2):e31041

Schröter, C., Ares, S., Morelli, L.G., Isakova, A., Hens, K., Soroldoni, D., Gajewski, M., Jülicher, F., Maerkl, S.J., Deplancke, B., and Oates, A.C. (2012) Topology and dynamics of the zebrafish segmentation clock core circuit. PLoS Biology. 10(7):e1001364

Herrgen, L., Ares, S., Morelli, L.G., Schröter, C., Jülicher, F., and Oates, A.C. (2010) Intercellular Coupling Regulates the Period of the Segmentation Clock. Current biology : CB. 20(14):1244-1253

Schröter, C., and Oates, A.C. (2010) Segment Number and Axial Identity in a Segmentation Clock Period Mutant. Current biology : CB. 20(14):1254-1258

Lee, H.C., Tseng, W.A., Lo, F.Y., Liu, T.M., and Tsai, H.J. (2009) FoxD5 mediates anterior-posterior polarity through upstream modulator Fgf signaling during zebrafish somitogenesis. Developmental Biology. 336(2):232-245

Walters, K.B., Dodd, M.E., Mathias, J.R., Gallagher, A.J., Bennin, D.A., Rhodes, J., Kanki, J.P., Look, A.T., Grinblat, Y., and Huttenlocher, A. (2009) Muscle degeneration and leukocyte infiltration caused by mutation of zebrafish fad24. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(1):86-99

Grosskurth, S.E., Bhattacharya, D., Wang, Q., and Lin, J.J. (2008) Emergence of Xin demarcates a key innovation in heart evolution. PLoS One. 3(8):e2857

Deniziak, M., Thisse, C., Rederstorff, M., Hindelang, C., Thisse, B., and Lescure, A. (2007) Loss of selenoprotein N function causes disruption of muscle architecture in the zebrafish embryo. Experimental cell research. 313(1):156-167

Riedel-Kruse, I.H., Müller, C., and Oates, A.C. (2007) Synchrony Dynamics During Initiation, Failure, and Rescue of the Segmentation Clock. Science (New York, N.Y.). 317(5846):1911-1915

Additional Citations (20):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

Thisse, B., Pflumio, S., Fürthauer, M., Loppin, B., Heyer, V., Degrave, A., Woehl, R., Lux, A., Steffan, T., Charbonnier, X.Q. and Thisse, C. (2001) Expression of the zebrafish genome during embryogenesis (NIH R01 RR15402). ZFIN Direct Data Submission.