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ZIRC
ZFIN ID: ZDB-GENE-040108-7
Gene Name: xin actin binding repeat containing 2a
Gene Symbol: xirp2a    Nomenclature History

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Previous Names: xirp2, sb:cb1045, wu:fc12g12, Xin beta6 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity and metal ion binding activity. Predicted to be involved in actin filament bundle assembly; heart development; and negative regulation of actin filament depolymerization. Predicted to localize to the cell junction. Is expressed in several structures, including fin; forebrain; musculature system; pericardial region; and somite. Orthologous to human XIRP2 (xin actin binding repeat containing 2).
Genome Resources: Alliance (1),  Gene:559746 (1),  Ensembl(GRCz11):ENSDARG00000071113 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12933 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26687 Point Mutation Unknown Unknown ENU
    sa40639 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-xirp2a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH xirp2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH xirp2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin cytoskeleton organization (more)
    Cellular Component cell junction (more)
    Molecular Function actin binding (more)
    GO Terms (all 8)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA xirp2a-201 (1)    Ensembl 10784
    xirp2a-202 (1)    Ensembl 4032
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-xirp polyclonal Rabbit WB 1
    Ab1-xirp2a polyclonal Rabbit 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM xirp2a No data available
    MARKER RELATIONSHIPS
    xirp2a Contained in: [BAC] DKEY-276L13 (order this)
    xirp2a Encodes: [EST] cb1045 (1), fc12g12
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005165785 (1) 10991 bp
    Genomic GenBank:BX511272 (1) 208912 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F8W4U4 (1) 3315 aa
    Sequence Clusters UniGene:78041 (1)
    Sequence Information (all 21)
    ORTHOLOGY for xirp2a ( Chr: 6 )
    CITATIONS (47)