ZFIN

ZFIN ID: ZDB-GENE-030902-5

ZFIN ID: ZDB-GENE-030902-5

CITATIONS (79 total)

Gene Name:	potassium channel tetramerisation domain containing 12.1
Gene Symbol:	kctd12.1

Powell, G.T., Faro, A., Zhao, Y., Stickney, H., Novellasdemunt, L., Henriques, P., Gestri, G., Redhouse White, E., Ren, J., Lu, W., Young, R.M., Hawkins, T.A., Cavodeassi, F., Schwarz, Q., Dreosti, E., Raible, D.W., Li, V.S.W., Wright, G.J., Jones, E.Y., Wilson, S.W. (2024) Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain. Science (New York, N.Y.). 384:573579573-579

Yao, Y., Baronio, D., Chen, Y.C., Jin, C., Panula, P. (2023) The Roles of Histamine Receptor 1 (hrh1) in Neurotransmitter System Regulation, Behavior, and Neurogenesis in Zebrafish. Molecular neurobiology. 60(11):6660-6675

Agostini, C., Bühler, A., Antico Calderone, A., Aadepu, N., Herder, C., Loosli, F., Carl, M. (2022) Conserved and diverged asymmetric gene expression in the brain of teleosts. Frontiers in cell and developmental biology. 10:1005776

Michel, L., Palma, K., Cerda, M., Lagadec, R., Mayeur, H., Fuentès, M., Besseau, L., Martin, P., Magnanou, E., Blader, P., Concha, M.L., Mazan, S. (2022) Diversification of habenular organization and asymmetries in teleosts: Insights from the Atlantic salmon and European eel. Frontiers in cell and developmental biology. 10:1015074

Choi, J.H., Duboue, E.R., Macurak, M., Chanchu, J.M., Halpern, M.E. (2021) Specialized neurons in the right habenula mediate response to aversive olfactory cues. eLIFE. 10:

Szenker-Ravi, E., Ott, T., Khatoo, M., de Bellaing, A.M., Goh, W.X., Chong, Y.L., Beckers, A., Kannesan, D., Louvel, G., Anujan, P., Ravi, V., Bonnard, C., Moutton, S., Schoen, P., Fradin, M., Colin, E., Megarbane, A., Daou, L., Chehab, G., Di Filippo, S., Rooryck, C., Deleuze, J.F., Boland, A., Arribard, N., Eker, R., Tohari, S., Ng, A.Y., Rio, M., Lim, C.T., Eisenhaber, B., Eisenhaber, F., Venkatesh, B., Amiel, J., Crollius, H.R., Gordon, C.T., Gossler, A., Roy, S., Attie-Bitach, T., Blum, M., Bouvagnet, P., Reversade, B. (2021) Discovery of a genetic module essential for assigning left-right asymmetry in humans and ancestral vertebrates. Nature Genetics. 54(1):62-72

Wang, G.T., Pan, H.Y., Lang, W.H., Yu, Y.D., Hsieh, C.H., Kuan, Y.S. (2021) Three-dimensional multi-gene expression maps reveal cell fate changes associated with laterality reversal of zebrafish habenula. Journal of neuroscience research. 99(6):1632-1645

Guglielmi, L., Bühler, A., Moro, E., Argenton, F., Poggi, L., Carl, M. (2020) Temporal control of Wnt signaling is required for habenular neuron diversity and brain asymmetry. Development (Cambridge, England). 147(6):

Messina, A., Boiti, A., Vallortigara, G. (2020) Asymmetric distribution of pallial-expressed genes in zebrafish (Danio rerio). The European journal of neuroscience. 53(2):362-375

Wu, C.S., Lu, Y.F., Liu, Y.H., Huang, C.J., Hwang, S.L. (2020) Zebrafish Cdx1b modulates epithalamic asymmetry by regulating ndr2 and lft1 expression. Developmental Biology. 470:21-36

Lekk, I., Duboc, V., Faro, A., Nicolaou, S., Blader, P., Wilson, S.W. (2019) Sox1a mediates the ability of the parapineal to impart habenular left-right asymmetry. eLIFE. 8:

Choi, J.H., Jeong, Y.M., Kim, S., Lee, B., Ariyasiri, K., Kim, H.T., Jung, S.H., Hwang, K.S., Choi, T.I., Park, C.O., Huh, W.K., Carl, M., Rosenfeld, J.A., Raskin, S., Ma, A., Gecz, J., Kim, H.G., Kim, J.S., Shin, H.C., Park, D.S., Gerlai, R., Jamieson, B.B., Kim, J.S., Iremonger, K.J., Lee, S.H., Shin, H.S., Kim, C.H. (2018) Targeted knockout of a chemokine-like gene increases anxiety and fear responses. Proceedings of the National Academy of Sciences of the United States of America. 115(5):E1041-E1050

Schredelseker, T., Driever, W. (2018) Bsx controls pineal complex development. Development (Cambridge, England). 145(13):

Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613

Beretta, C.A., Dross, N., Guglielmi, L., Bankhead, P., Soulika, M., Gutierrez-Triana, J.A., Paolini, A., Poggi, L., Falk, J., Ryu, S., Kapsimali, M., Engel, U., Carl, M. (2017) Early Commissural Diencephalic Neurons Control Habenular Axon Extension and Targeting. Current biology : CB. 27(2):270–278

Khuansuwan, S., Clanton, J.A., Dean, B.J., Patton, J.G., Gamse, J.T. (2016) A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex. Development (Cambridge, England). 143(14):2641-50

Noël, E.S., Momenah, T.S., Al-Dagriri, K., Al-Suwaid, A., Al-Shahrani, S., Jiang, H., Willekers, S., Oostveen, Y.Y., Chocron, S., Postma, A.V., Bhuiyan, Z.A., Bakkers, J. (2016) A zebrafish Loss-of-Function Model for Human CFAP53 Mutations Reveals its Specific Role in Laterality Organ Function. Human Mutation. 37(2):194-200

Kuan, Y.S., Roberson, S., Akitake, C.M., Fortuno, L., Gamse, J., Moens, C., Halpern, M.E. (2015) Distinct requirements for Wntless in habenular development. Developmental Biology. 406(2):117-28

Lagadec, R., Laguerre, L., Menuet, A., Amara, A., Rocancourt, C., Péricard, P., Godard, B.G., Celina Rodicio, M., Rodriguez-Moldes, I., Mayeur, H., Rougemont, Q., Mazan, S., Boutet, A. (2015) The ancestral role of nodal signalling in breaking L/R symmetry in the vertebrate forebrain. Nature communications. 6:6686

Dean, B.J., Erdogan, B., Gamse, J.T., Wu, S.Y. (2014) Dbx1b defines the dorsal habenular progenitor domain in the zebrafish epithalamus. Neural Development. 9:20

deCarvalho, T.N., Subedi, A., Rock, J., Harfe, B.D., Thisse, C., Thisse, B., Halpern, M.E., Hong, E. (2014) Neurotransmitter map of the asymmetric dorsal habenular nuclei of zebrafish. Genesis (New York, N.Y. : 2000). 52(6):636-55

Dreosti, E., Vendrell Llopis, N., Carl, M., Yaksi, E., and Wilson, S.W. (2014) Left-right asymmetry is required for the habenulae to respond to both visual and olfactory stimuli. Current biology : CB. 24(4):440-445

Garric, L., Ronsin, B., Roussigné, M., Booton, S., Gamse, J.T., Dufourcq, P., Blader, P. (2014) Pitx2c ensures habenular asymmetry by restricting parapineal cell number. Development (Cambridge, England). 141:1572-9

Lee, S., Page-McCaw, P., Gamse, J.T. (2014) Kctd12 and Ulk2 partner to regulate dendritogenesis and behavior in the habenular nuclei.. PLoS One. 9(10):1-7

Pavlou, S., Astell, K., Kasioulis, I., Gakovic, M., Baldock, R., van Heyningen, V., and Coutinho, P. (2014) Pleiotropic effects of Sox2 during the development of the zebrafish epithalamus. PLoS One. 9(1):e87546

Wu, S.Y., de Borsetti, N.H., Bain, E.J., Bulow, C.R., and Gamse, J.T. (2014) Mediator subunit 12 coordinates intrinsic and extrinsic control of epithalamic development. Developmental Biology. 385(1):13-22

Chandrasekar, G., Vesterlund, L., Hultenby, K., Tapia-Páez, I., and Kere, J. (2013) The Zebrafish Orthologue of the Dyslexia Candidate Gene DYX1C1 Is Essential for Cilia Growth and Function. PLoS One. 8(5):e63123

Colombo, A., Palma, K., Armijo, L., Mione, M., Signore, I.A., Morales, C., Guerrero, N., Meynard, M.M., Pérez, R., Suazo, J., Marcelain, K., Briones, L., Härtel, S., Wilson, S.W., and Concha, M.L. (2013) Daam1a mediates asymmetric habenular morphogenesis by regulating dendritic and axonal outgrowth. Development (Cambridge, England). 140(19):3997-4007

deCarvalho, T.N., Akitake, C.M., Thisse, C., Thisse, B., Halpern, M.E. (2013) Aversive cues fail to activate fos expression in the asymmetric olfactory-habenula pathway of zebrafish. Frontiers in neural circuits. 7:98

Lu, P.N., Lund, C., Khuansuwan, S., Schumann, A., Harney-Tolo, M., Gamse, J.T., and Liang, J.O. (2013) Failure in closure of the anterior neural tube causes left isomerization of the zebrafish epithalamus. Developmental Biology. 374(2):333-344

Noël, E.S., Verhoeven, M., Lagendijk, A.K., Tessadori, F., Smith, K., Choorapoikayil, S., den Hertog, J., and Bakkers, J. (2013) A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality. Nature communications. 4:2754

Ogawa, S., Ng, K.W., Ramadasan, P.N., Nathan, F.M., and Parhar, I.S. (2012) Habenular Kiss1 Neurons Modulate the Serotonergic System in the Brain of Zebrafish. Endocrinology. 153(5):2398-2407

de Borsetti, N.H., Dean, B.J., Bain, E.J., Clanton, J.A., Taylor, R.W., and Gamse, J.T. (2011) Light and melatonin schedule neuronal differentiation in the habenular nuclei. Developmental Biology. 358(1):251-61

Doll, C.A., Burkart, J.T., Hope, K.D., Halpern, M.E., and Gamse, J.T. (2011) Subnuclear development of the zebrafish habenular nuclei requires ER translocon function. Developmental Biology. 360(1):44-57

Domenichini, A., Dadda, M., Facchin, L., Bisazza, A., and Argenton, F. (2011) Isolation and Genetic Characterization of Mother-of-Snow-White, a Maternal Effect Allele Affecting Laterality and Lateralized Behaviors in Zebrafish. PLoS One. 6(10):e25972

Taylor, R.W., Qi, J.Y., Talaga, A.K., Ma, T.P., Pan, L., Bartholomew, C.R., Klionsky, D.J., Moens, C.B., and Gamse, J.T. (2011) Asymmetric inhibition of ulk2 causes left-right differences in habenular neuropil formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(27):9869-9878

Kang, N., Ro, H., Park, Y., Kim, H.T., Huh, T.L., and Rhee, M. (2010) Seson, a novel zinc finger protein, controls cilia integrity for the LR patterning during zebrafish embryogenesis. Biochemical and Biophysical Research Communications. 401(2):169-174

Chen, Y.C., Cheng, C.H., Chen, G.D., Hung, C.C., Yang, C.H., Hwang, S.P., Kawakami, K., Wu, B.K., and Huang, C.J. (2009) Recapitulation of zebrafish sncga expression pattern and labeling the habenular complex in transgenic zebrafish using green fluorescent protein reporter gene. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(3):746-754

Facchin, L., Argenton, F., and Bisazza, A. (2009) Lines of Danio rerio selected for opposite behavioural lateralization show differences in anatomical left-right asymmetries. Behavioural brain research. 197(1):157-165

Regan, J.C., Concha, M.L., Roussigne, M., Russell, C., and Wilson, S.W. (2009) An Fgf8-dependent bistable cell migratory event establishes CNS asymmetry. Neuron. 61(1):27-34

Roussigné, M., Bianco, I.H., Wilson, S.W., and Blader, P. (2009) Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei. Development (Cambridge, England). 136(9):1549-1557

Serluca, F.C., Xu, B., Okabe, N., Baker, K., Lin, S.Y., Sullivan-Brown, J., Konieczkowski, D.J., Jaffe, K.M., Bradner, J.M., Fishman, M.C., and Burdine, R.D. (2009) Mutations in zebrafish leucine-rich repeat-containing six-like affect cilia motility and result in pronephric cysts, but have variable effects on left-right patterning. Development (Cambridge, England). 136(10):1621-1631

Toyama, R., Chen, X., Jhawar, N., Aamar, E., Epstein, J., Reany, N., Alon, S., Gothilf, Y., Klein, D.C., and Dawid, I.B. (2009) Transcriptome analysis of the zebrafish pineal gland. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(7):1813-1826

Bianco, I.H., Carl, M., Russell, C., Clarke, J.D., and Wilson, S.W. (2008) Brain asymmetry is encoded at the level of axon terminal morphology. Neural Development. 3:9

Snelson, C.D., Burkart, J.T., and Gamse, J.T. (2008) Formation of the asymmetric pineal complex in zebrafish requires two independently acting transcription factors. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(12):3538-3544

Snelson, C.D., Santhakumar, K., Halpern, M.E., and Gamse, J.T. (2008) Tbx2b is required for the development of the parapineal organ. Development (Cambridge, England). 135(9):1693-1702

Aizawa, H., Goto, M., Sato, T., and Okamoto, H. (2007) Temporally regulated asymmetric neurogenesis causes left-right difference in the zebrafish habenular structures. Developmental Cell. 12(1):87-98

Amack, J.D., Wang, X., and Yost, H.J. (2007) Two T-box genes play independent and cooperative roles to regulate morphogenesis of ciliated Kupffer's vesicle in zebrafish. Developmental Biology. 310(2):196-210

Carl, M., Bianco, I.H., Bajoghli, B., Aghaallaei, N., Czerny, T., and Wilson, S.W. (2007) Wnt/Axin1/beta-Catenin Signaling Regulates Asymmetric Nodal Activation, Elaboration, and Concordance of CNS Asymmetries. Neuron. 55(3):393-405

Inbal, A., Kim, S.H., Shin, J., and Solnica-Krezel, L. (2007) Six3 represses nodal activity to establish early brain asymmetry in zebrafish. Neuron. 55(3):407-415

Kuan, Y.S., Gamse, J.T., Schreiber, A.M., and Halpern, M.E. (2007) Selective asymmetry in a conserved forebrain to midbrain projection. Journal of experimental zoology. Part B, Molecular and developmental evolution. 308(5):669-678

Kuan, Y.S., Yu, H.H., Moens, C.B., and Halpern, M.E. (2007) Neuropilin asymmetry mediates a left-right difference in habenular connectivity. Development (Cambridge, England). 134(5):857-865

Schottenfeld, J., Sullivan-Brown, J., and Burdine, R.D. (2007) Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw. Development (Cambridge, England). 134(8):1605-1615

Aizawa, H., Bianco, I.H., Hamaoka, T., Miyashita, T., Uemura, O., Concha, M.L., Russell, C., Wilson, S.W., and Okamoto, H. (2005) Laterotopic Representation of Left-Right Information onto the Dorso-Ventral Axis of a Zebrafish Midbrain Target Nucleus. Current biology : CB. 15(3):238-243

Gamse, J.T., Kuan, Y.S., Macurak, M., Brosamle, C., Thisse, B., Thisse, C., and Halpern, M.E. (2005) Directional asymmetry of the zebrafish epithalamus guides dorsoventral innervation of the midbrain target. Development (Cambridge, England). 132(21):4869-4881

Song, H.D., Sun, X.J., Deng, M., Zhang, G.W., Zhou, Y., Wu, X.Y., Sheng, Y., Chen, Y., Ruan, Z., Jiang, C.L., Fan, H.Y., Zon, L.I., Kanki, J.P., Liu, T.X., Look, A.T., and Chen, Z. (2004) Hematopoietic gene expression profile in zebrafish kidney marrow. Proceedings of the National Academy of Sciences of the United States of America. 101(46):16240-16245

Gamse, J.T., Thisse, C., Thisse, B., and Halpern, M.E. (2003) The parapineal mediates left-right asymmetry in the zebrafish diencephalon. Development (Cambridge, England). 130:1059-1068

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (21):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

Moens, C.B. and ZFIN Staff (2009) Curation of TILLING Database Links. ZFIN Direct Data Submission.

ZIRC and ZFIN Staff (2008) Mutant and Transgenic Line Submissions 2008. ZFIN Direct Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2003) Submission and Curation of Mutant and Transgenic Lines. ZFIN Direct Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

Thisse, B., Pflumio, S., Fürthauer, M., Loppin, B., Heyer, V., Degrave, A., Woehl, R., Lux, A., Steffan, T., Charbonnier, X.Q. and Thisse, C. (2001) Expression of the zebrafish genome during embryogenesis (NIH R01 RR15402). ZFIN Direct Data Submission.