Publication	Data		Fish	Anatomy
Holowiecki et al., 2020	Fig. 1		pbx4b557/b557	atrium nppa expression increased amount, abnormal atrium bulbous, abnormal cardiac ventricle cardiac muscle cell increased amount, abnormal cardiac ventricle elongated, abnormal
	Fig. 2		pbx4b557/b557	cardiac ventricle malformed, abnormal whole organism myh7 expression increased amount, abnormal
	Fig. 3		pbx4b557/b557	bulbus arteriosus cardiac muscle cell increased amount, abnormal
	Fig. 4		pbx4b557/b557 ,   fb7Tg + MO2-pbx4 + MO3-pbx4	cardiac muscle myoblast cdkn1a expression decreased amount, abnormal cardiac muscle myoblast cdkn2c expression decreased amount, abnormal cardiac muscle myoblast cell population proliferation increased occurrence, abnormal whole organism nkx2.5 expression increased amount, abnormal
	Fig. 5		pbx4b557/b557	cardiac muscle myoblast ltbp3 expression decreased amount, abnormal presumptive cardiac ventricle primitive heart tube mef2cb expression increased amount, abnormal
	Fig. 6		pbx4b557/b557	pharyngeal arch 3-7 embryonic blood vessel endothelial progenitor cell tie1 expression absent, abnormal pharyngeal arch 3-7 embryonic blood vessel endothelial progenitor cell absent, abnormal
	Fig. 7		pbx4b557/b557; fb9Tg	embryonic blood vessel endothelial progenitor cell mislocalised, abnormal
Farr et al., 2018	Fig. 1		pbx4b557/b557 (AB)	cardiac muscle tissue morphogenesis decreased process quality, abnormal embryonic heart tube morphogenesis decreased process quality, abnormal heart tube malformed, abnormal myocardium malformed, abnormal whole organism pbx4 expression decreased amount, abnormal
	Fig. 3		pbx4b557/b557 (AB)	cardiac ventricle malformed, abnormal embryonic heart tube morphogenesis decreased process quality, abnormal heart morphogenesis decreased process quality, abnormal heart tube malformed, abnormal myocardium malformed, abnormal myocardium mislocalised medially, abnormal
Selland et al., 2018	Fig. 4		pbx4b557/b557	rhombomere 3 egr2b expression decreased amount, abnormal rhombomere 3 egr2b expression decreased distribution, abnormal rhombomere 3 epha4a expression decreased amount, abnormal rhombomere 3 epha4a expression decreased distribution, abnormal rhombomere 3 decreased size, abnormal rhombomere 3 morphology, abnormal
Kao et al., 2015	Fig. 1		pbx4b557/b557 (AB)	blood accumulation atrium anatomical region, abnormal pericardium edematous, abnormal
	Fig. 2		pbx4b557/b557 (AB)	anterior lateral plate mesoderm myh7 expression decreased amount, abnormal anterior lateral plate mesoderm myl7 expression decreased amount, abnormal anterior lateral plate mesoderm tnnt2a expression decreased amount, abnormal anterior lateral plate mesoderm cardiac muscle cell myh7 expression decreased amount, abnormal anterior lateral plate mesoderm cardiac muscle cell myl7 expression decreased amount, abnormal anterior lateral plate mesoderm cardiac muscle cell tnnt2a expression decreased amount, abnormal cardiac muscle cell myh6 expression decreased amount, abnormal cardioblast migration to the midline involved in heart rudiment formation decreased occurrence, abnormal myocardium nppa expression decreased amount, abnormal
	Fig. 3		pbx4b557/b557 (AB)	lateral plate mesoderm hand2 expression increased distribution, abnormal
	Fig. 4		pbx4b557/b557 (AB) ,   pbx4b557/b557; s958Tg; sd12Tg	atrium cardiac muscle cell increased amount, abnormal bulbus arteriosus development process quality, abnormal bulbus arteriosus smooth muscle elnb expression spatial pattern, abnormal cardiac muscle cell increased amount, abnormal cardiac ventricle cardiac muscle cell increased amount, abnormal cardiac ventricle morphology, abnormal heart tube ltbp3 expression decreased amount, abnormal heart tube ltbp3 expression increased distribution, abnormal pectoral fin tbx18 expression absent, abnormal proepicardial cluster tbx18 expression absent, abnormal proepicardium development decreased occurrence, abnormal secondary heart field specification decreased occurrence, abnormal
Erickson et al., 2011	Fig. 2		pbx4b557/b557	hindbrain tshz3b expression decreased amount, abnormal midbrain tshz3b expression decreased amount, abnormal
	Fig. 6		pbx4b557/b557	rhombomere 3 egr2b expression decreased amount, abnormal
Teoh et al., 2010	Fig. 5		WT + MO5-pbx4	swim bladder physical object quality, abnormal
diIorio et al., 2007	Fig. 2		pbx4b557/b557	endocrine pancreas mislocalised anteriorly, abnormal
	Fig. 3		pbx4b557/b557	endoderm development disrupted, abnormal endoderm morphology, abnormal pectoral fin bud aplastic, abnormal
	Fig. 4		pbx4b557/b557	endocrine pancreas mislocalised anteriorly, abnormal
	Fig. 5		pbx4b557/b557	endocrine pancreas mislocalised anteriorly, abnormal
	Fig. 6		pbx4b557/b557	exocrine pancreas mislocalised anteriorly, abnormal liver mislocalised anteriorly, abnormal
Erickson et al., 2007	Fig. 1		pbx4b557/b557	midbrain hindbrain boundary malformed, abnormal optic tectum decreased size, abnormal
Phenotype Annotation (1994-2006)	Fig. for (b557)		pbx4b557/b557	brain quality, abnormal heart quality, abnormal hindbrain quality, abnormal neural crest quality, abnormal pectoral fin quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal
	Fig. for (hi1126)		pbx4hi1126Tg	eye decreased size, abnormal pectoral fin quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal surface structure quality, abnormal yolk quality, abnormal
	Fig. for (hi933)		pbx4hi933Tg	eye decreased size, abnormal pectoral fin quality, abnormal pharyngeal arch 3-7 skeleton quality, abnormal surface structure quality, abnormal yolk quality, abnormal
Yu et al., 2005	Fig. 1		pbx4b557/b557	cranial neural crest cell mislocalised, abnormal neural crest cell migration disrupted, abnormal
	Fig. 4		pbx4b557/b557	cranial neural crest cell mislocalised, abnormal neural crest cell migration disrupted, abnormal
	Fig. 5		pbx4b557/b557	cranial neural crest cell mislocalised, abnormal neural crest cell migration disrupted, abnormal
Amsterdam et al., 2004	text only		pbx4hi933Tg/hi933Tg	eye decreased size, abnormal fin bud aplastic, abnormal head decreased size, abnormal pectoral fin aplastic, abnormal pericardium edematous, abnormal
Deflorian et al., 2004	Fig. 3		WT + MO1-pbx4	eye decreased size, abnormal head decreased size, abnormal pericardium edematous, abnormal swim bladder inflation arrested, abnormal
Waskiewicz et al., 2001	Fig. 5		pbx4b557/b557	Mauthner neuron absent, abnormal rhombomere 4 RoL2 mislocalised, abnormal RoL2 increased amount, abnormal
	Fig. 6		pbx4b557/b557	ceratobranchial cartilage absent, abnormal ceratohyal cartilage decreased size, abnormal hyosymplectic cartilage decreased size, abnormal Meckel's cartilage decreased size, abnormal Meckel's cartilage fused with ceratohyal cartilage, abnormal palatoquadrate cartilage decreased size, abnormal palatoquadrate cartilage fused with hyosymplectic cartilage, abnormal
Pöpperl et al., 2000	Fig. 5		pbx4b557/b557	pectoral fin bud aplastic, abnormal thymus aplastic, abnormal