FIGURE

Fig. 6

ID

ZDB-FIG-200416-9

Publication

Holowiecki et al., 2020 - Pbx4 limits heart size and fosters arch artery formation through partitioning second heart field progenitors and restricting proliferation

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Fig. 6

ECs in pPAAs are absent in lzr mutants. (A-D) IHC for mCherry (red) and EGFP (green) in WT and lzr mutant embryos with the kdrl:mCherry (ECs) and myl7:EGFP (CMs) transgenes at 72 and 80 hpf. Views in A and B are lateral with anterior left. Views in C and D are ventral with anterior up. Numbers designate the PAAs. ORA, opercular artery. White arrows and brackets indicate anterior arches. (E,F) ISH for tie1 at 36 hpf. Views are lateral with anterior left. WT (n=17), lzr (n=9). Asterisks denote aggregates of EC progenitors within developing posterior arches. White line marks tie1+ cells that extend to the dorsal aorta in lzr mutants. Scale bars: 100 µm.

Expression Data

Gene:	tie1
Fish:	WT pbx4^b557/b557
Anatomical Term:	pharyngeal arch 3-7 embryonic blood vessel endothelial progenitor cell
Stage:	Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pbx4^b557/b557
Observed In:	pharyngeal arch 3-7 embryonic blood vessel endothelial progenitor cell
Stage Range:	Prim-25 to Long-pec

Phenotype Detail

Acknowledgments

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