Fig. 9

The stacked column chart illustrates the percentage of developing embryos with multiple deformities in neural tube (multiple neural tube defects) and isolated neural tube defect at 120 hpf in groups exposed to decitabine 1mM (n=20). The multiple neural tube defects noted were curly up-tail curvature + tail curvature (5%), kyphosis + wavy neural tube (5%), kyphosis + wavy neural tube + scoliosis (5%), kyposis + wavy neural tube + broadened neural tube + scoliosis (5%), lordosis + split spine + neural tube curvature (5%), kyphosis + tail curvature + split spine (5%), split spine + scoliosis + neural tube curvature (5%), split spine + fragmented neural tube + neural tube curvature (5%), kyphosis + neural tube curvature (5%), kyphosis + wavy neural tube + split spine (5%), kyphosis + split spine (5%), kyphosis + neural tube curvature (5%), split spine + scoliosis (5%), split spine + neural tube curvature (5%), split spine + tail curvature (5%), curly up-tail curvature + wavy neural tube (5%), neural tube curvature + craniofacial malformation (5%), lordosis + tail curvature (5%), fragmented neural tube + lordosis + tail curvature (5%). The remaining 5% of developing embryos suffered from isolated neural tube curvature (INTD)