FIGURE

Fig. 3

ID

ZDB-FIG-250421-123

Publication

Xiao et al., 2025 - Deficiency of psmb6 suppresses proteasome activity and promotes apoptosis in larval zebrafish brain

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Fig. 3

Increased apoptosis of midbrain cells in psmb6 mutants. (A) The top fifteen pathways with significant differences from RNA sequencing analysis were identified. (B) Verify sequencing results by Q-PCR at 3.5 dpf.∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001, Student's t-test. (C) Detect the ubiquitinated protein by WB at 3.5 dpf, internal reference: α-β-tubulin. (D) In situ cell death detection for 3.5 dpf psmb6 mutants (red fluorescence). DAPI (blue). Scale bars: 50 μm. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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