FIGURE

FIGURE 4

ID

ZDB-FIG-240118-20

Publication

Chen et al., 2024 - Angiopoietin 1 and integrin beta 1b are vital for zebrafish brain development

Other Figures

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FIGURE 4

Decreased proliferation and increased gfap intensity in angpt1^–/– and itgb1b^–/– larvae. Maximum intensity projections of confocal z-stack images were made by immunostaining GFAP following the EdU proliferation assay in 3-dpf genotyped larvae. EdU labeling results shown in (A)angpt1^+/+(D)angpt1^–/–(G)itgb1b^+/+ and (J)itgb1b^–/– larval brains. gfap-immunoreactivity results shown in (B)angpt1^+/+(E)angpt1^–/–(H)itgb1b^+/+ and (K)itgb1b^–/– larval brains. The merge images of Edu-labeling and gfap-positive are shown in (C)angpt1^+/+(F)angpt1^–/–(I)itgb1b^+/+ and (L)itgb1b^–/– larval brains. Proliferating cells are indicated in green, and gfap-positive signals are in magenta. N = 5 per genotyped group. Scale bars are 200 μm.

Expression Data

Gene:	gfap
Antibody:	zrf-1
Fish:	WT angpt1^{sa14264/sa14264} itgb1b^mi371/mi371
Anatomical Terms:	forebrain hindbrain
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	angpt1^{sa14264/sa14264} itgb1b^mi371/mi371
Observed In:	brain proliferative region forebrain hindbrain
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.