ZFIN Image: Chen et al., 2024, FIGURE 4

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Figure Caption

FIGURE 4

Decreased proliferation and increased gfap intensity in angpt1^–/– and itgb1b^–/– larvae. Maximum intensity projections of confocal z-stack images were made by immunostaining GFAP following the EdU proliferation assay in 3-dpf genotyped larvae. EdU labeling results shown in (A)angpt1^+/+(D)angpt1^–/–(G)itgb1b^+/+ and (J)itgb1b^–/– larval brains. gfap-immunoreactivity results shown in (B)angpt1^+/+(E)angpt1^–/–(H)itgb1b^+/+ and (K)itgb1b^–/– larval brains. The merge images of Edu-labeling and gfap-positive are shown in (C)angpt1^+/+(F)angpt1^–/–(I)itgb1b^+/+ and (L)itgb1b^–/– larval brains. Proliferating cells are indicated in green, and gfap-positive signals are in magenta. N = 5 per genotyped group. Scale bars are 200 μm.

Acknowledgments

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