FIGURE

F

ID

ZDB-FIG-220131-581

Publication

Wu et al., 2021 - Sensing of mycobacterial arabinogalactan by galectin-9 exacerbates mycobacterial infection

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Galectin‐9 is essential for AG‐induced expression of MMPs

Immunoblots of cell lysates of THP‐1 cells stably transfected with scrambled shRNA or shRNA targeting galectin‐9.

B–D

qPCR analysis of Mmps including Mmp9 (B), Mmp10 (C), and Mmp12 (D) mRNA from control or Galectin‐9 knockdown THP‐1 cells stimulated with AG (1 μg/ml) for indicated times.

Diagram showing the gRNA‐targeting genome sites.

Identification of galectin‐9 KO mice with PCR.

Data information: Data in (B–D) are means ± SD averaged from n = 3 independent experiments performed with technical triplicates, and each symbol represents the mean of technical triplicates. Data in (A, F) are representative of at least n = 2 independent experiments. Two‐way ANOVA followed by Tukey's post hoc test (B–D) was used for statistical analysis, respectively. ns, not significant; *P < 0.05; ****P < 0.0001.

Source data are available online for this figure.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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