FIGURE

Figure 5

ID

ZDB-FIG-201003-53

Publication

Knuth et al., 2020 - Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish

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Figure 5

Metabolic dyshomeostasis in VDD AT. (A) Elevated expression of lipid transporters in VDD liver 6 mpf. Decreased expression of fabp11a in VDD AT 6 mpf. (B) Elevated expression of lypolitic factors in VDD liver 6 mpf, with a decrease in lipea and lipeb in VDD AT. (C) Greater abundance of erk1/2 protein in VDD liver 6 mpf, with a decreased in p-erk1/2. (D) Suppression of mitochondrial biogenesis in VDD AT compared to VDD liver 6 mpf. (E) Elevated expression of lipogenic factors in VDD liver 6 mpf. Elevated expression of pparg and srebf1 in VDD AT 6 mpf with a decrease in pparaa and cebpa. *See also Figure S3.

Expression Data

Genes:	apoba apoc2 apoc4 cebpa fabp4a lipea lipeb mapk3 pparaa pparg ppargc1a srebf1
Fish:	AB
Condition:	nutrient decreased
Anatomical Terms:	adipose tissue liver
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	nutrient decreased
Observed In:	adipose tissue liver
Stage:	Adult

Phenotype Detail

Acknowledgments

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