FIGURE

Fig. 4

ID

ZDB-FIG-190711-18

Publication

Ghersi et al., 2019 - bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish

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Fig. 4

bif1 affects definitive hematopoiesis. (A) Bright-field images from O-dianisidine-stained embryos at 3?dpf. These embryos are injected with a control morpholino or a morpholino against bif1. (B) Percentage of embryos showing absent/low (gray) or high (black) levels of hemoglobin. Data are mean±s.e.m. (C-F) Whole-mount in situ hybridization for gata1 at 4?dpf (C), rag1 at 5?dpf (D), cmyb at 4?dpf (E), gata2b at 26?hpf, runx1 at 28?hpf and cmyb at 48?hpf (F), in embryos injected with control morpholino (ctrl-MO) or morpholino against bif1 (bif1-MO).

Expression Data

Genes:	gata1a gata2b myb rag1 runx1
Fish:	AB AB + MO1-bif1.1
Knockdown Reagent:	MO1-bif1.1
Anatomical Terms:	caudal hematopoietic tissue dorsal aorta thymus
Stage Range:	Prim-5 to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-bif1.1
Knockdown Reagent:	MO1-bif1.1
Observed In:	caudal hematopoietic tissue dorsal aorta nucleate erythrocyte thymus
Stage Range:	Prim-5 to Day 5

Phenotype Detail

Acknowledgments

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