FIGURE

Fig. 5

ID
ZDB-FIG-181024-9
Publication
Xu et al., 2018 - Fox proteins are modular competency factors for facial cartilage and tooth specification
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Fig. 5

Fox genes are required for chondrogenic gene expression downstream of Sox9a. (A) Fluorescence in situ hybridizations show that barx1+ pre-cartilage condensations of the first two arches are unaltered in foxc1a; foxc1b double mutants (c1a?/?; c1b?/?) and foxf1; foxf2a; foxf2b triple mutants (f1?/?; f2a?/?; f2b?/?) compared with sibling controls. (B,C) Schematic of the cartilaginous facial skeleton shows regions examined by fluorescence in situ hybridization. Maximum intensity projections for foxc1a; foxc1b mutants at 56?hpf (B) and representative sections for foxf1; foxf2a; foxf2b mutants at 72?hpf (C) show expression of the chondrogenic genes col2a1a, matn1, matn4 or acana (green) relative to sox9a (red). Arrows indicate regions in which sox9a+ cells have reduced chondrogenic gene expression relative to sibling controls. Numbers denote proportions of embryos with displayed patterns. Scale bars: 50??m.
Expression Data
Genes: (all 6)
Fish:
Anatomical Terms:
Stage Range: Prim-25 to Protruding-mouth

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage Range: Long-pec to Protruding-mouth

Phenotype Detail
Acknowledgments
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