FIGURE

Fig. 3

ID
ZDB-FIG-181024-7
Publication
Xu et al., 2018 - Fox proteins are modular competency factors for facial cartilage and tooth specification
Other Figures
All Figure Page
Back to All Figure Page
Fig. 3

Loss of midline cartilage and pharyngeal teeth in Fox-F mutants. (A) Ventral views of dissected facial skeletons, with cartilage in blue and bones and teeth in red. Schematics show affected elements in color. Bb, basibranchials; Bh, basihyal; Ch, ceratohyal; M, Meckel's; Ptp, pterygoid process. (B) Lateral views of wild-type sibling control and foxf1; foxf2a; foxf2b triple mutant at 5 dpf. Mutants show anterior truncation of the head (arrow). (C) Dissections of neurocranial cartilages show loss of the trabecular cartilages (Tr, arrow) in foxf1; foxf2a; foxf2b triple mutants. Ep, ethmoid plate. (D) Sagittal sections through the tooth-forming seventh arch of a wild-type sibling control and foxf1; foxf2a; foxf2b triple mutant at 4 dpf. All teeth (3V1, 4V2 and 5V1) are missing in mutants. c, chorda; cb5, ceratobranchial 5; ov, otic vesicle. (E,F) Whole-mount in situ hybridizations show loss of dlx2b (E) and fgf3 (F) in the developing tooth regions (arrows) of foxf1; foxf2a; foxf2b triple mutants. Numbers denote proportions of embryos with displayed phenotypes or expression patterns. Scale bars: 25 μm.

Expression Data
Genes:
Fish:
Anatomical Term:
Stage: Long-pec

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage Range: Long-pec to Day 5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development