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ZIRC
ZFIN ID: ZDB-GENE-050208-221
Gene Name: aggrecan a
Gene Symbol: acana    Nomenclature History

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Previous Names: agca, agc1, im:7146049

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity and hyaluronic acid binding activity. Involved in outflow tract morphogenesis. Predicted to localize to the extracellular matrix. Is expressed in bulbus arteriosus; cranium; pectoral fin; and pharyngeal arch 3-7. Orthologous to human ACAN (aggrecan).
Genome Resources: Alliance (1),  Gene:497505 (1),  Ensembl(GRCz11):ENSDARG00000035891 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7281 Point Mutation Unknown Premature Stop ENU
sa31591 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40999 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-acana
    1
    MO1-acana N/A 1
    MO2-acana N/A 1
    DISEASE ASSOCIATED WITH acana HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    osteochondritis dissecans Alliance Short stature and advanced bone age, with or without early-onset osteoarthritis and/or osteochondritis dissecans 165800
    Spondyloepimetaphyseal dysplasia, aggrecan type 612813
    ?Spondyloepiphyseal dysplasia, Kimberley type 608361
    DISEASE ASSOCIATED WITH acana VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process outflow tract morphogenesis (more)
    Cellular Component extracellular matrix (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acana-201 (1)    Ensembl 6000
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acana No data available
    MARKER RELATIONSHIPS
    acana Contained in: [BAC] DKEY-56P7 (1) (order this)
    acana Encodes: [EST] IMAGE:7146049 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005166485 (1) 6450 bp
    Genomic GenBank:AL929208 (1) 189608 bp
    Select Tool
    Polypeptide UniProtKB:F1QDA1 (1) 1547 aa
    Sequence Clusters UniGene:89851 (1)
    Sequence Information (all 21)
    ORTHOLOGY for acana ( Chr: 7 )
    CITATIONS (33)