FIGURE

Fig. 5

ID

ZDB-FIG-180918-26

Publication

Xing et al., 2018 - Mutational analysis of dishevelled genes in zebrafish reveals distinct functions in embryonic patterning and gastrulation cell movements

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Fig. 5

The expression of organizer genes is not affected in MZdvl2;MZdvl3a mutants.

In situ hybridization analysis of the expression patterns of goosecoid, chordin, and tbxta at dome stage. Animal pole viewed embryos with dorsal region on the right. (A) Schematic representation for the analysis of MZdvl2;MZdvl3a embryos. (B-F) Representative images show similar expression patterns of goosecoid in WT embryos and in different mutants. (G) Knockdown of ß-catenin2 strongly inhibits goosecoid expression. (H-L) Similar expression patterns of chordin in WT embryos and all indicated mutants. (M) Knockdown of ß-catenin2 blocks chordin expression. (N-R) The expression patterns of tbxta are similar between WT embryos and different mutants. (S) Knockdown of ß-catenin2 has no effect on tbxta expression. Scale bar: (B-J) 400 μm.

Expression Data

Genes:	chrd gsc tbxta
Fish:	WT WT + MO1-ctnnb2 dvl2^sdu15/+; dvl3a^sdu16/sdu16 dvl2^sdu15/sdu15; dvl3a^sdu16/sdu16
Knockdown Reagent:	MO1-ctnnb2
Anatomical Term:	whole organism
Stage:	Dome

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-ctnnb2
Knockdown Reagent:	MO1-ctnnb2
Observed In:	whole organism
Stage:	Dome

Phenotype Detail

Acknowledgments

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