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Fig. S11

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ZDB-FIG-180529-8

Publication

Sánchez-Iranzo et al., 2018 - Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration

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Fig. S11

Genetic ablation of tbx5a-derived ventricular cardiomyocytes in individualized fish.

a tbx5a⁺ ventricular cardiomyocytes were genetically ablated in tbx5a:CreER^T2;vmhcl:loxP-tagBFP-loxP-mCherry-NTR double transgenic zebrafish. Recombination was induced by administration of 4- Hydroxytamoxifen (4-OHT). Fish were individualised, imaged at 4 days postfertilisation (dpf) and cell ablation was induced by administration of Metronidazole (Mtz) from 4 to 7 dpf. b,f Maximum projection of confocal z-stacks of 4 dpf embryos. c–e, g–i Hearts dissected from the same fish at 42 dpf. at, atrium; ba, bulbus arteriosus; v, ventricle. Scale bars, b, f 25 μm, c, g 100 μm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.