FIGURE

Fig. 1

ID

ZDB-FIG-180524-13

Publication

S�nchez-Iranzo et al., 2018 - Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration

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Fig. 1

Expression profile of tbx5a-positive cardiomyocytes in embryonic zebrafish hearts. a?f Whole-mount immunofluorescence of tbx5a:GFP;myl7:mbmCherry double transgenic zebrafish hearts at 32 a?c (n?=?5/5) and 56?hours postfertilisation (hpf) d?f (n?=?3/3). g?l Confocal optical sections of tbx5a:GFP;myl7:mbmCherry hearts at 72?hpf g?i (n?=?5/5), 4?days postfertilisation (dpf) j?l (n?=?9/9), and 5 dpf (m?o; n?=?6/6). GFP (green) labels tbx5a⁺?cells and mCherry (red) marks cells expressing the pan-myocardial marker myosin light chain 7 (myl7). Shown are ventral views, cranial is to the top. At 32?hpf all cardiomyocytes are tbx5a:GFP⁺ but at 56, 72?hpf, 4, and 5?dpf tbx5a:GFP^? cardiomyocytes can be observed in the distal ventricle (arrowheads). The atrioventricular canal and large portions of the atrium are also GFP⁺. at, atrium; v, ventricle; Scale bars, 10??m

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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