ZFIN ID: ZDB-FIG-171107-7
Chen et al., 2017 - Impairment of Cargo Transportation Caused by gbf1 Mutation Disrupts Vascular Integrity and Causes Hemorrhage in Zebrafish Embryos.. The Journal of biological chemistry   292(6):2315-2327 Full text @ J. Biol. Chem.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Prim-25 to Long-pec
PHENOTYPE:
Fish:
Conditions:
Knockdown Reagents:
Observed In:
Stage Range: Prim-25 to Long-pec

Fig. 9 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
arcn1a s843Tg standard conditions High-pec endothelial cell RTPCR
s843Tg ; gbf1tsu3994/tsu3994 standard conditions High-pec endothelial cell RTPCR
arcn1b s843Tg standard conditions High-pec endothelial cell RTPCR
s843Tg ; gbf1tsu3994/tsu3994 standard conditions High-pec endothelial cell RTPCR
badb s843Tg standard conditions Prim-25 endothelial cell RTPCR
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Prim-25 endothelial cell RTPCR
baxb s843Tg standard conditions Prim-25 endothelial cell RTPCR
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Prim-25 endothelial cell RTPCR
bcl2a s843Tg standard conditions Prim-25 endothelial cell RTPCR
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Prim-25 endothelial cell RTPCR
copa s843Tg standard conditions High-pec endothelial cell RTPCR
s843Tg ; gbf1tsu3994/tsu3994 standard conditions High-pec endothelial cell RTPCR
copg2 s843Tg standard conditions High-pec endothelial cell RTPCR
s843Tg ; gbf1tsu3994/tsu3994 standard conditions High-pec endothelial cell RTPCR
ddit3 s843Tg standard conditions Prim-25 endothelial cell RTPCR
High-pec endothelial cell RTPCR
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Prim-25 endothelial cell RTPCR
High-pec endothelial cell RTPCR
EGFP s843Tg standard conditions Prim-25 trunk vasculature blood vessel endothelium IHC
Long-pec trunk vasculature blood vessel endothelium IHC
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Prim-25 trunk vasculature blood vessel endothelium IHC
Long-pec trunk vasculature blood vessel endothelium IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
gbf1tsu3994/tsu3994 control Long-pec vasculature hemorrhagic, abnormal
gbf1tsu3994/tsu3994 chemical treatment by environment: GSK2656157 Long-pec vasculature hemorrhagic, ameliorated
gbf1tsu3994/tsu3994 chemical treatment by environment: tauroursodeoxycholic acid Long-pec vasculature hemorrhagic, ameliorated
gbf1tsu3994/tsu3994 + MO1-baxb standard conditions Long-pec vasculature hemorrhagic, ameliorated
gbf1tsu3994/tsu3994 + MO1-ddit3 standard conditions Long-pec vasculature hemorrhagic, abnormal
gbf1tsu3994/tsu3994 + MO3-badb standard conditions Long-pec vasculature hemorrhagic, ameliorated
gbf1tsu3994/tsu3994 + MO3-badb chemical treatment by environment: tauroursodeoxycholic acid Long-pec vasculature hemorrhagic, ameliorated
gbf1tsu3994/tsu3994 + MO5-tp53 standard conditions Long-pec vasculature hemorrhagic, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Prim-25 endothelial cell ddit3 expression increased amount, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Prim-25 endothelial cell badb expression increased amount, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Prim-25 endothelial cell baxb expression increased amount, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Prim-25 intersegmental vessel blood vessel endothelial cell apoptotic, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Prim-25 trunk vasculature blood vessel endothelial cell apoptotic, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions High-pec endothelial cell copg2 expression increased amount, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions High-pec endothelial cell arcn1a expression increased amount, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions High-pec endothelial cell copa expression increased amount, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions High-pec endothelial cell ddit3 expression increased amount, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Long-pec intersegmental vessel blood vessel endothelial cell apoptotic, abnormal
s843Tg ; gbf1tsu3994/tsu3994 standard conditions Long-pec trunk vasculature blood vessel endothelial cell apoptotic, abnormal
Full text @ J. Biol. Chem.