FIGURE

Fig. 9

ID

ZDB-FIG-150504-25

Publication

Kantarci et al., 2015 - Tfap2a Promotes Specification and Maturation of Neurons in the Inner Ear through Modulation of Bmp, Fgf and Notch Signaling

Other Figures

All Figure Page

Back to All Figure Page

Fig. 9

Tfap2a regulates SAG development non-autonomously.

(A-D) Whole-mounts (dorsal up, anterior left) and cross-sections (just posterior to utricular macula, medial to the left) showing both bright-field and corresponding fluorescent images of +/+ host embryos (A, B) and hs:tfap2a host embryos stained for etv5b expression (blue) and showing transplanted wild-type donor cells (red). Positions of wild-type cells that fail to express etv5b are highlighted with arrows in (C, D). (E) Summary of mosaic analysis showing the number of +/+ or hs:tfap2a host embryos examined and the number of +/+ donor cells expressing etv5b over the total number of donor cells that populated the ventral half of the otic vesicle. (F-H) Expression of etv5b at 26 hpf in a control (F), a DM-treated hs:tfap2a embryo (G) and DM-treated wild-type embryo (H). All specimens were treated with 1% DMSO and heat-shocked at 24 hpf. (I-L) Expression of bmp7a at 26 hpf in a control (I, J), tfap2a^-/- mutant (K) and hs:tfap2a embryo (L). Wild-type and hs:tfap2a embryos were heat shocked at 24 hpf.

Expression Data

Genes:	bmp7a etv5b
Fish:	AB tfap2a^m819/m819 x24Tg
Conditions:	heat shock chemical treatment: dorsomorphin, heat shock
Anatomical Terms:	otic vesicle otic vesicle anterior region otic vesicle posterior region otic vesicle ventro-lateral region
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB x24Tg
Condition:	chemical treatment: dorsomorphin, heat shock
Observed In:	otic vesicle fibroblast growth factor receptor signaling pathway
Stage:	Prim-5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.