Gene

bmp7a

ID
ZDB-GENE-000208-25
Name
bone morphogenetic protein 7a
Symbol
bmp7a Nomenclature History
Previous Names
  • bmp7 (1)
  • fb83f09
  • snailhouse
  • snh
  • wu:fb83f09 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Exhibits identical protein binding activity and protein heterodimerization activity. Involved in several processes, including determination of bilateral symmetry; negative regulation of endodermal cell fate specification; and post-anal tail morphogenesis. Predicted to localize to extracellular space. Is expressed in several structures, including epiphysis; gastrula cell; margin; prechordal plate; and tail bud. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human BMP7 (bone morphogenetic protein 7).
Genome Resources
Note
None
Expression
All Expression Data
22 figures from 18 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
19 figures from 14 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bmp7a Human Ortholog
No data available
Associated With bmp7a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017948 Transforming growth factor beta, conserved site
Domain IPR001111 TGF-beta, propeptide
Domain IPR001839 Transforming growth factor-beta, C-terminal
Family IPR015615 Transforming growth factor-beta-related
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine-knot cytokine TGF-beta, propeptide Transforming growth factor beta, conserved site Transforming growth factor-beta, C-terminal Transforming growth factor-beta-related
UniProtKB:F1Q926 284
UniProtKB:Q9PTF9 432
UniProtKB:Q0PQ43 103
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations