FIGURE

Fig. 5

ID

ZDB-FIG-130730-5

Publication

Wilfinger et al., 2013 - Cell type and tissue specific function of islet genes in zebrafish pancreas development

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Fig. 5

isl2a does not contribute to endocrine cell formation. (A–C) Immunostainings for Ins (green) and Isl-proteins (red) in the pancreatic region of control (A), isl1 mutant (B), and isl1 mutant/MO^isl2a injected embryos (C) at 48 hpf. (D) Quantification of ins mRNA positive cells and examples of corresponding in situ stains for ins mRNA in isl1 mutants (E, G), and in isl1 mutant, MO^isl2a injected embryos (F, H) at 30 hpf (E, F) and 72 hpf (G, H). Bars show mean+SEM.

Expression Data

Genes:	mnx2a pdx1 prss1 ptf1a
Fish:	WT isl1a^sa29/sa29 + MO1-isl2b + MO3-isl2a
Knockdown Reagents:	MO1-isl2b MO3-isl2a
Anatomical Terms:	anterior pancreatic bud exocrine pancreas extrapancreatic duct
Stage Range:	Long-pec to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 378(1), Wilfinger, A., Arkhipova, V., and Meyer, D., Cell type and tissue specific function of islet genes in zebrafish pancreas development, 25-37, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.