Gene
ptf1a
- ID
- ZDB-GENE-030616-579
- Name
- pancreas associated transcription factor 1a
- Symbol
- ptf1a Nomenclature History
- Previous Names
-
- Ptfa (1)
- si:zc142h2.2
- zgc:112216
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Acts upstream of or within several processes, including amacrine cell differentiation; exocrine pancreas development; and positive regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including exocrine cell; intestinal bulb primordium; mid intestine; nervous system; and pancreatic system. Human ortholog(s) of this gene implicated in pancreatic agenesis. Orthologous to human PTF1A (pancreas associated transcription factor 1a).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 76 figures from 49 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu536 (18 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|
|
UniProtKB:Q7ZSX3
|
265 |
Interactions and Pathways
No data available
Plasmids
No data available