ZFIN ID: ZDB-FIG-110214-4
Radosevic et al., 2011 - Her9 represses neurogenic fate downstream of Tbx1 and retinoic acid signaling in the inner ear. Development (Cambridge, England)   138(3):397-408 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibody:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage: Prim-5

Fig. 4 her9 inhibits Cdkns and controls cell proliferation. (A-D) In situ hybridization of cdkn1bl (A,B) and cdkn1c (C,D) in wild-type (A,C) and her9-MO-injected (B,D) zebrafish embryos at 24 hpf. Arrow indicates posterolateral expansion of cdkn1bl expression. (E-H) Transverse sections of wild-type and Her9 morphant embryos stained by in situ hybridization for her9 (blue) and immunohistochemistry with anti-pH3 (green). (I) Proportion of pH3-positive cells counted inside and outside the her9-expression domain in wild-type and Her9-depleted embryos. Error bars indicate mean + s.e.m. *P=0.001. A-D and E-H are at the same magnification.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
cdkn1ba AB standard conditions Prim-5 otic vesicle ISH
AB + MO2-her9 standard conditions Prim-5 otic vesicle postero-lateral region ISH
cdkn1ca AB standard conditions Prim-5 otic vesicle ISH
AB + MO2-her9 standard conditions Prim-5 otic vesicle ISH
her9 AB standard conditions Prim-5 otic vesicle ISH
AB + MO2-her9 standard conditions Prim-5 otic vesicle ISH
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-h3 IHC AB standard conditions Prim-5 otic vesicle
IHC AB + MO2-her9 standard conditions Prim-5 otic vesicle
Phenotype Details No data available
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development