FIGURE

Fig. 5

ID

ZDB-FIG-101021-23

Publication

Kwon et al., 2010 - Identification of early requirements for preplacodal ectoderm and sensory organ development

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Fig. 5

Knockdown of competence factors impairs preplacodal specification.

(A–C) Expression of preplacodal markers at 10.5 hpf in (A) foxi1/gata3 double morphants, (B) tfap2a/c double morphants, (C) foxi1/gata3/tfap2a/c quadruple morphants (4-MO). Note the complete loss of preplacodal markers in C. (D) Expression of krox20, p63, P-smad and sizzled during gastrulation in foxi1/gata3/tfap2a/c quadruple morphants. Morphology of a live quadruple morphant at 30 hpf is also shown. (E) Expression of six4.1 and eya1 in p63 morphants alone or in combination with tfap2a/c-MO or foxi1/gata3-MO. All images show lateral views with dorsal to the right and anterior up, except for the live specimen in (D), which shows a lateral view with anterior to the left.

Expression Data

Genes:	dlx3b egr2b eya1 six4b szl tp63
Fish:	WT + MO3-tp63 WT + MO2-foxi1 + MO2-gata3 WT + MO2-tfap2c + MO4-tfap2a WT + MO2-foxi1 + MO2-gata3 + MO3-tp63 WT + MO2-tfap2c + MO3-tp63 + MO4-tfap2a WT + MO2-foxi1 + MO2-gata3 + MO2-tfap2c + MO4-tfap2a
Knockdown Reagents:	MO2-foxi1 MO2-gata3 MO2-tfap2c MO3-tp63 MO4-tfap2a
Anatomical Terms:	ectoderm hindbrain neural plate
Stage:	1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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