ZFIN ID: ZDB-GENE-030530-1
Gene Name: sizzled
Gene Symbol: szl
Sequence Ontology ID : SO:0000704

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Previous Names: mercedes (1), mes (1), ogo, ogon, sfrp

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(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have Wnt-protein binding activity; involved in several processes, including determination of dorsal identity, developmental pigmentation, and negative regulation of BMP signaling  ...
GENE EXPRESSION
All Expression Data: 18 figures from 9 publications
Directly Submitted Expression Data: 6 figures (5 images) from Thisse et al., 2005 [eu695]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
rk1 Point Mutation Donor Splice Site of Intron 1 Premature Stop ENU
sa24765 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30384 Point Mutation Unknown Splice Site ENU
    tm305 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tz209 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 15 figures from 7 publications
    Observed in:
    DISEASE ASSOCIATED WITH szl HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH szl VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein stabilization (more)
    Cellular Component integral component of membrane (more)
    Molecular Function protein binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001134 (1)
  • InterPro:IPR015526 (1)
  • InterPro:IPR020067 (1)
  • InterPro:IPR036790 (1)
  • PROSITE:PS50038 (1)
  • PROSITE:PS50189 (1)
  • Pfam:PF01392 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM szl No data available
    MARKER RELATIONSHIPS
    szlEncodes: [EST] eu695 (1)
    [cDNA] MGC:136522 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_181663 (1)
    Genomic GenBank:DU644791 (1) 190bp
    Polypeptide UniProtKB:Q504J9 (1) 289aa
    Sequence Clusters UniGene:84079 (1)
    Sequence Information (all 18)
    OTHER szl GENE PAGES
  • Alliance (1)
  • Gene:353294 (1)
  • Ensembl(GRCz11):ENSDARG00000099637 (1)
  • ORTHOLOGY for szl (Chr: 25)
    CITATIONS (63)