Gene

szl

ID
ZDB-GENE-030530-1
Name
sizzled
Symbol
szl Nomenclature History
Previous Names
  • mercedes (1)
  • mes (1)
  • ogo
  • ogon
  • sfrp
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have Wnt-protein binding activity. Involved in several processes, including determination of dorsal identity; negative regulation of BMP signaling pathway; and protein stabilization. Predicted to localize to extracellular space. Is expressed in ectoderm; mesoderm; periderm; and tail bud.
Genome Resources
Note
None
Expression
All Expression Data
23 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
15 figures from 7 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With szl Human Ortholog
No data available
Associated With szl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001134 Netrin domain
Domain IPR020067 Frizzled domain
Domain IPR041772 Sizzled, cysteine-rich domain
Family IPR015526 Frizzled/secreted frizzled-related protein
Homologous_superfamily IPR036790 Frizzled cysteine-rich domain superfamily
Domain Details Per Protein
Protein Length Frizzled cysteine-rich domain superfamily Frizzled domain Frizzled/secreted frizzled-related protein Netrin domain Sizzled, cysteine-rich domain
UniProtKB:Q504J9 289
UniProtKB:Q7SX78 282
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations