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ZFIN ID: ZDB-FIG-090113-105
Chakraborty et al., 2009 - Loss of ribosomal protein L11 affects zebrafish embryonic development through a p53-dependent apoptotic response. PLoS One   4(1):e4152 Full text @ PLoS One
Knockdown Reagents:
Observed In:
Stage: Prim-5

Fig. S5 Morphological observation and TUNEL staining of embryos injected simultaneously with rpl5, rpl11, and rpl23 MOs.(A) Lateral views of 24 hpf embryos simultaneously injected with the three MOs. Severe morphological deformities with almost a complete absence of brain subdivisions (black arc) were observed in the morphants. (B) Dorsal and lateral views of the head region of 24 hpf embryos showing extensive apoptosis (blue dots). Scale bars: A, 250 μm; B, 100 μm.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-rpl11 + MO1-rpl23 + MO1-rpl5a standard conditions Prim-5 apoptotic process increased occurrence, abnormal
Prim-5 brain deformed, abnormal
Prim-5 brain morphogenesis disrupted, abnormal
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One