FIGURE

Fig. 7

ID
ZDB-FIG-080312-6
Publication
Vinothkumar et al., 2008 - Sequential and cooperative action of Fgfs and Shh in the zebrafish retina
Other Figures
All Figure Page
Back to All Figure Page
Fig. 7

Several Fgfs are required for transgene expression in the retina. Embryos injected with either MO-fgf3 or MO-fgf8 show no effect on the transgene expression in the retina (A, B) while those injected with a mixture of MO-fgf8 and MO-fgf3 block the transgene expression completely (D). Control embryos injected with mismatch MO-fgf3 and mismatch MO-fgf8 have a normal GFP expression pattern (C). Embryos injected with MO-fgf19 show initiation at the ventral nasal patch (arrow) and subsequent spread is blocked (F). Control embryos injected with mismatch MO-fgf19 had a normal GFP expression pattern (E). Confocal pictures at 48 hpf with anterior to the top. L, lens. Scale bar, 50 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 314(1), Vinothkumar, S., Rastegar, S., Takamiya, M., Ertzer, R., and Strähle, U., Sequential and cooperative action of Fgfs and Shh in the zebrafish retina, 200-214, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.