ZFIN Image: Vinothkumar et al., 2008, Fig. 7

Image

Figure Caption

Fig. 7 Several Fgfs are required for transgene expression in the retina. Embryos injected with either MO-fgf3 or MO-fgf8 show no effect on the transgene expression in the retina (A, B) while those injected with a mixture of MO-fgf8 and MO-fgf3 block the transgene expression completely (D). Control embryos injected with mismatch MO-fgf3 and mismatch MO-fgf8 have a normal GFP expression pattern (C). Embryos injected with MO-fgf19 show initiation at the ventral nasal patch (arrow) and subsequent spread is blocked (F). Control embryos injected with mismatch MO-fgf19 had a normal GFP expression pattern (E). Confocal pictures at 48 hpf with anterior to the top. L, lens. Scale bar, 50 μm.

Acknowledgments

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Reprinted from Developmental Biology, 314(1), Vinothkumar, S., Rastegar, S., Takamiya, M., Ertzer, R., and Strähle, U., Sequential and cooperative action of Fgfs and Shh in the zebrafish retina, 200-214, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.