FIGURE

Fig. 5

ID

ZDB-FIG-080211-48

Publication

Veldman et al., 2007 - Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration

Other Figures

(all 8)

All Figure Page

Back to All Figure Page

Fig. 5

Quantitative RT-PCR time course of gene expression in the retina following optic nerve crush injury. Quantitative real-time RT-PCR was used to measure mRNA levels in the retina at various time points following optic nerve crush injury as compared to uninjured retina. Expression of GAPDH was used to normalize all samples. SOCS3a (A), SOCS3b (B), Sox11a (C), Sox11b (D), KLF6a (E), and KLF7a (F) are all induced by 1-day post-injury (dpi), peak around 2?6 dpi and return to basal levels by 12?24 dpi. The dotted line denotes basal uninjured levels in each graph.

Expression Data

Genes:	klf6a klf7b socs3a socs3b sox11a sox11b (all 6)
Fish:	WT
Condition:	physical alteration: anatomical structure
Anatomical Term:	retina
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 312(2), Veldman, M.B., Bemben, M.A., Thompson, R.C., and Goldman, D., Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration, 596-612, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.