Gene

socs3b

ID
ZDB-GENE-040426-2528
Name
suppressor of cytokine signaling 3b
Symbol
socs3b Nomenclature History
Previous Names
  • zgc:77038
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in phosphatidylinositol phosphorylation. Predicted to localize to phosphatidylinositol 3-kinase complex. Is expressed in eye; heart; lateral line ganglion; and segmental plate. Human ortholog(s) of this gene implicated in atopic dermatitis 4. Orthologous to human SOCS3 (suppressor of cytokine signaling 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Lawir et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With socs3b Human Ortholog
No data available
Associated With socs3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001496 SOCS box domain
Domain IPR035863 SOCS3, SH2 domain
Family IPR028414 Suppressor of cytokine signalling 3
Homologous_superfamily IPR036036 SOCS box-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length SH2 domain SH2 domain superfamily SOCS3, SH2 domain SOCS box domain SOCS box-like domain superfamily Suppressor of cytokine signalling 3
UniProtKB:Q6NYJ2 210
UniProtKB:U3JAZ8 197
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations