Gene
sox11a
- ID
- ZDB-GENE-980526-395
- Name
- SRY-box transcription factor 11a
- Symbol
- sox11a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in brain development; camera-type eye development; and negative regulation of smoothened signaling pathway. Predicted to localize to nucleus. Is expressed in several structures, including mesoderm; nervous system; neural keel; neural rod; and somite. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 9. Orthologous to human SOX11 (SRY-box transcription factor 11).
- Genome Resources
- Note
- None
- All Expression Data
- 33 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb237 (25 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Tsurusaki et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Coffin-Siris syndrome 9 | Alliance | Coffin-Siris syndrome 9 | 615866 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | High mobility group box domain | High mobility group box domain superfamily | Transcription factor SOX-11 | Transcription factor SOX-12/11/4 |
---|---|---|---|---|---|
UniProtKB:Q9I9C8
|
354 | ||||
UniProtKB:Q1RM26
|
336 | ||||
UniProtKB:Q9YH23
|
354 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
sox11a-201
(1)
|
3298 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl