FIGURE

Fig. 7

ID

ZDB-FIG-060828-6

Publication

Eaton et al., 2006 - The zebrafish bHLH PAS transcriptional regulator, single-minded 1 (sim1), is required for isotocin cell development

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Fig. 7

Expression patterns of nkx2.2a, dlx2a, titf1a, and shh are unchanged in sim1 morphants. Nkx2.2a, dlx2a, titf1a, and shh mRNA was detected by ISHH in embryos that were injected with Morpholino oligonucleotides (MO). A,C,E,G: Embryos injected with 0.5 ng of a 4-base mismatch "control" sim1 MO. B,D,F,H: Embryos injected with 0.5 ng of sim1 MO (e.g., sim1 morphants, MO^sim1). Dorsal is up and anterior to the left. The age of the embryos is indicated on each panel in hours post-fertilization (hpf). The probes are indicated on each panel. The location of the optic recess (or) is indicated by a black bar. t, telencephalon; m, midbrain; hy, hypothalamus.

Expression Data

Genes:	dlx2a nkx2.2a nkx2.4b shha
Fish:	WT + MO1-sim1a
Knockdown Reagent:	MO1-sim1a
Anatomical Terms:	diencephalon hypothalamus telencephalon
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-sim1a
Knockdown Reagent:	MO1-sim1a
Observed In:	embryo development eye head
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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