CRISPR

CRISPR1-gmds

ID
ZDB-CRISPR-230809-1
Name
CRISPR1-gmds
Previous Names
None
Target
Sequence
5' - GGTTGGAACCCTTCGGCTGC - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
nfl2 gmds
Expression
Gene expression in Wild Types + CRISPR1-gmds
No data available
Phenotype
Phenotype resulting from CRISPR1-gmds
No data available
Phenotype of all Fish created by or utilizing CRISPR1-gmds
Phenotype Fish Conditions Figures
brain vasculature hemorrhagic, ameliorated gmdsnfl2/nfl2 (AB) chemical treatment by injection: L-fucose Fig. 2 with image from Fowler et al., 2021
brain vasculature hemorrhagic, ameliorated gmdsnfl2/nfl2 (AB) chemical treatment by injection: GDP-L-fucose Fig. 2 with image from Fowler et al., 2021
brain vasculature hemorrhagic, abnormal gmdsnfl2/nfl2 (AB) standard conditions Fig. 1 with image,  Fig. 2 with image,  Fig. 3 with image from Fowler et al., 2021
post-vent region curved, abnormal gmdsnfl2/nfl2 (AB) standard conditions Fig. 1 with image from Fowler et al., 2021
brain vasculature hemorrhagic, exacerbated gmdsnfl2/nfl2 (AB) chemical treatment by environment: DAPT Fig. 3 with image from Fowler et al., 2021
thigmotaxis decreased process quality, abnormal gmdsnfl2/nfl2 (AB) standard conditions Fig. 1 with image from Fowler et al., 2021
bulbus arteriosus vascular associated smooth muscle cell tagln expression decreased distribution, abnormal gmdsnfl2/nfl2 (AB) standard conditions Fig. S5 from Fowler et al., 2021
pharyngeal arch vascular associated smooth muscle cell decreased amount, abnormal gmdsnfl2/nfl2; ca2Tg (AB) standard conditions Fig. 4 with image from Fowler et al., 2021
bulbus arteriosus vascular associated smooth muscle cell decreased amount, abnormal gmdsnfl2/nfl2; ca2Tg (AB) standard conditions Fig. 4 with image from Fowler et al., 2021
brain vasculature hemorrhagic, exacerbated gmdsnfl2/nfl2 + MO1-fcsk + MO4-tp53 (AB) control Fig. 2 with image from Fowler et al., 2021
Citations
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